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Large language model-driven Socratic questioning for endodontic case analysis: A randomised controlled trial.

Wenjing Liu1, Xueying Huang1, Minkang Zhan1

  • 1Stomatological Hospital, Southern Medical University, Guangzhou, China.

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|July 9, 2026
PubMed
Summary

A large language model (LLM)-based Socratic questioning system effectively trained dental students in endodontic case analysis. This AI tool achieved similar outcomes to traditional case-based learning (CBL) while significantly reducing faculty teaching time.

Keywords:
artificial intelligencecase‐based learningclinical reasoningendodontic educationlarge language modelssocratic questioning

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Area of Science:

  • Dental Education
  • Artificial Intelligence in Medicine
  • Endodontics

Background:

  • Endodontic education faces challenges in providing sufficient clinical reasoning practice due to resource limitations.
  • Case-based learning (CBL) is a valuable method but can be resource-intensive for faculty.
  • Developing innovative educational tools is crucial for enhancing structured clinical reasoning skills.

Purpose of the Study:

  • To develop and evaluate a large language model (LLM)-based Socratic questioning system for endodontic case-analysis training.
  • To compare the feasibility, educational outcomes, learner experience, and faculty time of the LLM system against traditional CBL.
  • To assess the potential of AI to supplement existing endodontic educational resources.

Main Methods:

  • A randomized controlled trial involving 79 third-year dental students comparing an AI-guided group (n=40) with a CBL group (n=39).
  • The AI system utilized a Socratic questioning engine, case-analysis scoring, and adaptive recommendations.
  • Both groups underwent a one-hour intervention before simulated case assessment; outcomes included scores and faculty time.

Main Results:

  • Both AI and CBL groups showed significant within-group improvement in case-analysis scores.
  • No statistically significant difference was found in post-training total scores or score improvement between the AI and CBL groups.
  • The AI intervention required substantially less direct faculty teaching time per student (0.026 hours vs. 0.45 hours for CBL).

Conclusions:

  • An LLM-based Socratic questioning system is feasible for endodontic simulated case-analysis training.
  • The AI system demonstrated comparable short-term educational outcomes to faculty-led CBL.
  • The LLM system offers a valuable supplementary tool to address resource constraints in endodontic education by reducing faculty workload.