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Related Experiment Videos

Malnutrition Is Common in Cyclic Vomiting Syndrome: A Prospective Study Using Validated Nutritional Assessment Tools.

Thangam Venkatesan1, Praveen S Goday2, Saranya Arumugam3

  • 1Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University, Columbus, OH, USA. Thangam.Venkatesan@osumc.edu.

Digestive Diseases and Sciences
|July 9, 2026
PubMed
Summary

Most adults with cyclic vomiting syndrome (CVS) are at risk of malnutrition, despite potential overweight or obesity. Early nutritional assessment by a Registered Dietitian Nutritionist (RDN) is crucial for managing this condition.

Keywords:
Body mass indexCyclic vomitingMalnutritionNutrition screening

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Area of Science:

  • Gastroenterology
  • Nutritional Science
  • Clinical Medicine

Background:

  • Cyclic vomiting syndrome (CVS) frequently impacts nutritional status due to recurrent nausea and vomiting.
  • Systematic data on nutritional status in adults with CVS are limited.

Purpose of the Study:

  • To evaluate the nutritional status of adults diagnosed with cyclic vomiting syndrome (CVS).
  • To assess the effectiveness of validated screening tools in identifying malnutrition risk in CVS patients.

Main Methods:

  • A prospective study involving 80 adults diagnosed with CVS according to Rome IV criteria.
  • Nutritional status assessed using Patient-Generated Subjective Global Assessment Short Form (PG-SGA-SF), PG-SGA by a Registered Dietitian Nutritionist (RDN), and Malnutrition Screening Tool (MST).

Main Results:

  • 70% of participants were at risk of malnutrition based on PG-SGA-SF, with 51% identified by MST.
  • Despite malnutrition risk, 27% were obese and 20% overweight; BMI did not differentiate nutritional status.
  • The PG-SGA-SF showed high sensitivity (100%) and specificity (71%) for detecting malnutrition.

Conclusions:

  • The majority of adults with CVS exhibit malnutrition, necessitating referral to an RDN.
  • Body Mass Index (BMI) is not a reliable screening tool for malnutrition in CVS.
  • Further research is needed to understand the mechanisms contributing to obesity in CVS.