Related Experiment Video
Updated: Jul 12, 2026
04:32
Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
Published on: June 28, 2018
Ventilator-associated pneumonia prevention: Past, present, perspective
Marc Leone1, Ludivine Marecal1, Adrien Bouglé2
1Department of Anaesthesia and Intensive Care Unit, Nord Hospital, Assistance Publique Hôpitaux de Marseille, Aix Marseille Université, Marseille, France.
Journal of Critical Care
|July 9, 2026
Summary
Preventing ventilator-associated pneumonia (VAP) is crucial for critically ill patients. This review examines VAP prevention strategies over decades, highlighting persistent challenges and future directions for reducing infection rates.
Area of Science:
- Critical Care Medicine
- Infectious Disease Prevention
- Respiratory Therapy
Background:
- Ventilator-associated pneumonia (VAP) is a significant complication in intensive care units.
- Despite advancements, VAP incidence remains high, negatively affecting patient outcomes.
- Effective VAP prevention is essential for improving the management of critically ill patients.
Purpose of the Study:
- To review the historical evolution of VAP prevention strategies.
- To analyze recent meta-analyses on VAP prevention efficacy.
- To forecast future trends in VAP prevention.
Main Methods:
- Literature review focusing on VAP prevention.
- Analysis of recent meta-analyses and clinical studies.
- Synthesis of evidence to identify trends and predict future developments.
Main Results:
- VAP prevention strategies have evolved significantly over recent decades.
- Despite efforts, VAP incidence remains a persistent challenge in mechanical ventilation.
- Recent evidence suggests ongoing refinement of preventive measures is necessary.
Conclusions:
- Continuous evaluation and adaptation of VAP prevention protocols are vital.
- Future strategies may involve novel approaches to mitigate VAP risk.
- Reducing VAP incidence remains a priority in critical care settings.
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