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Related Concept Videos

Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
Veins of Head and Neck01:19

Veins of Head and Neck

The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...

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Related Experiment Videos

Risk Factors for Early Deep Vein Thrombosis After Free-Flap Reconstruction for Head and Neck Cancer Despite Routine

ZhongYi Sun1, JingJing Li2, PengFei Zhao3

  • 1Department Head, Department of Dentistry, Shanghai Songjiang District Sijing Hospital.

Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
|July 9, 2026
PubMed
Summary

Deep vein thrombosis (DVT) after head and neck cancer surgery is linked to larger tumor size and longer operations. Laboratory changes suggest a complex clotting process contributing to early DVT risk.

Related Experiment Videos

Area of Science:

  • Oncology
  • Vascular Surgery
  • Hematology

Background:

  • Deep vein thrombosis (DVT) is a significant complication following head and neck cancer (HNC) surgery with free-flap reconstruction.
  • Routine anticoagulation does not fully prevent early postoperative DVT.

Purpose of the Study:

  • To identify factors associated with very early DVT in HNC patients undergoing free-flap reconstruction.
  • To understand the predictors of DVT within 72 hours post-surgery.

Main Methods:

  • Retrospective cohort study of 276 HNC patients undergoing radical resection and free-flap reconstruction.
  • Analysis of demographic, clinical, treatment-related, and perioperative laboratory factors, including platelet indices.
  • Multivariable logistic regression to identify independent risk factors for early DVT.

Main Results:

  • 14 patients (5.1%) developed DVT within 72 hours postoperatively.
  • Tumor size >3.5 cm (OR=4.64) and operative time >450 minutes (OR=3.72) were independent risk factors for early DVT.
  • Patients with DVT showed decreased platelet count, plateletcrit, antithrombin III, and thromboelastography reaction time, with increased D-dimer and fibrin degradation products.

Conclusions:

  • Larger tumor size and prolonged operative duration are independent risk factors for early DVT after HNC surgery.
  • Laboratory parameter changes indicate a multifactorial thrombotic process involving coagulation activation and platelet consumption.
  • These findings may assist in early risk stratification for DVT in this patient population.