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Related Concept Videos

Fixation and Sectioning01:03

Fixation and Sectioning

Two basic types of preparation are used to visualize specimens with a light microscope: wet mounts and fixed specimens.
The simplest type of preparation is the wet mount, in which the specimen is placed in a drop of liquid on the slide. A liquid specimen can be directly deposited on the slide using a dropper. Solid specimens, such as skin scraping, can be placed on the slide before adding a drop of liquid to prepare the wet mount. Sometimes the liquid is simply water, but stains are often added...
Eccentric Loading01:16

Eccentric Loading

Eccentric loading is a crucial concept in the study of structural engineering and mechanics, particularly when analyzing the stability and stress distribution in columns. Unlike centric loading, where the force is applied along the centroidal axis, causing uniform compression, eccentric loading occurs when a force is applied off-center. This off-center application introduces not only direct compressive stress but also bending stress, significantly influencing the column's behavior under load.
Eccentricity of an Ellipse01:27

Eccentricity of an Ellipse

An ellipse is a fundamental conic section defined by the constant sum of distances from any point on its curve to two fixed points, known as the foci. This geometric property can be physically demonstrated using a pencil, string, and two pins. By anchoring the string at both ends and maintaining it taut with a pencil, one can trace the outline of an ellipse.The shape and extent of the ellipse are determined by its eccentricity, e, defined as the ratio of the distance between the center and a...
Eccentric Axial Loading in a Plane of Symmetry01:16

Eccentric Axial Loading in a Plane of Symmetry

Eccentric axial loading occurs when an axial load is applied away from the centroidal axis of a structural member. This scenario is common in engineering, where structural elements may not be directly aligned due to various design or functional requirements.
General Case of Eccentric Axial Loading01:12

General Case of Eccentric Axial Loading

Unsymmetrical bending occurs when the bending moment applied to a structural member does not align with its principal axis. This misalignment leads to complex stress distributions and deflection patterns that differ from symmetrical bending, which are essential for designing structures to withstand different loading conditions.
Consider a member subjected to equal and opposite forces that are applied along a line that does not coincide with the member's neutral axis. In unsymmetrical bending,...
Design of Columns under an Eccentric Load01:21

Design of Columns under an Eccentric Load

Designing columns to withstand eccentric loads is a critical aspect of structural engineering, ensuring structures can support off-center loads without failure. This design process must account for the additional normal stresses introduced by eccentric loading, which can significantly influence a column's stress distribution and overall stability. An eccentric load applied to a column induces normal stresses that can be conceptualized as a combination of stresses due to an equivalent centric...

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Eccentric fixation.

Seyed Saber Sahihalnasab1, Amir Golmakani1, Seyed Alireza Mohamadi1

  • 1Department of Optometry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Clinical & Experimental Optometry
|July 9, 2026
PubMed
Summary
This summary is machine-generated.

Eccentric fixation (EF) is a visual adaptation for maintaining binocular vision despite foveal damage. Modern treatments leveraging neuroplasticity show promise in restoring foveal fixation and visual function.

Keywords:
Abnormal retinal correspondencebinocular visioneccentric fixationfoveal integrity testneurobehavioral adaptation

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Area of Science:

  • Neuroscience
  • Ophthalmology
  • Visual Science

Background:

  • Eccentric fixation (EF) is a compensatory visual adaptation to foveal damage or developmental disorders like amblyopia and strabismus.
  • It enables continued binocular vision but often results in reduced visual acuity.

Purpose of the Study:

  • To review current knowledge on eccentric fixation (EF).
  • Highlight its role as a neurobehavioral adaptation, developmental mechanisms, diagnostic advancements, and treatment strategies.

Main Methods:

  • Review of pathophysiological, neuroscience, and functional imaging studies.
  • Analysis of advanced diagnostic techniques (microperimetry, OCT fixation shift, Foveal Integrity Test).
  • Evaluation of evolving treatment approaches from traditional exercises to modern biofeedback and virtual reality.

Main Results:

  • EF involves retinotopic map alterations, cortical plasticity, and eye movement changes.
  • Advanced diagnostics enable precise assessment of fixation characteristics.
  • Treatments utilizing neuroplasticity and active participation are most effective for restoring foveal fixation.

Conclusions:

  • Eccentric fixation is a structural compensatory process.
  • Understanding EF mechanisms aids in designing individualized treatments.
  • Future research should focus on optimizing neuroplasticity-based interventions for improved visual outcomes.