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Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

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Published on: August 18, 2020

Multidimensional social cognitive profiles: implications for adolescent internalizing psychopathology.

Victoria Guazzelli Williamson¹, Nicholas B Allen², Jennifer H Pfeifer²

¹University of Oregon, Eugene, OR 97403, USA; University of Pittsburgh, Pittsburgh, PA 15216, USA; University of Pittsburgh Medical Center, Pittsburgh, PA 15216, USA.

Trends in Cognitive Sciences

|July 9, 2026

Summary

Adolescent mental health is linked to social cognition development. Unique social cognitive profiles, characterized by specific dimensions, may increase risk for internalizing disorders, especially when inflexible.

Keywords:

adolescence anxiety depression mentalizing metaperception self

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Last Updated: Jul 12, 2026

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

Area of Science:

Developmental psychology
Clinical psychology
Neuroscience

Background:

Adolescence is a critical period for internalizing mental health disorders.
Higher-order social cognition is crucial during adolescence but often overlooked.
Social cognition involves processing information about oneself and others.

Purpose of the Study:

To propose a framework for understanding social cognition profiles in adolescence.
To investigate the link between social cognitive profiles and internalizing psychopathology.
To identify dimensions characterizing social cognition development.

Main Methods:

Characterizing social cognition profiles across four dimensions: Propensity, Degree, Positivity, and Negativity.
Examining the association between these profiles and internalizing psychopathology risk.
Considering the role of cognitive accuracy and contextual flexibility.

Main Results:

Protracted social cognition development leads to individualized profiles.
Specific profiles (high Propensity, Degree, Negativity; low Positivity) may increase risk.
Decreased accuracy and inflexible application of profiles exacerbate risk.

Conclusions:

Social cognitive profiles offer a novel perspective on adolescent internalizing disorders.
These profiles may be useful for stratifying, predicting, and targeting interventions.
Further research is needed to validate the clinical utility of these social cognitive profiles.