Related Experiment Video

Updated: Jul 12, 2026

Multiplex Immunofluorescence Combined with Spatial Image Analysis for the Clinical and Biological Assessment of the Tumor Microenvironment
06:05

Multiplex Immunofluorescence Combined with Spatial Image Analysis for the Clinical and Biological Assessment of the Tumor Microenvironment

Published on: June 2, 2023

Discovery of dynamic tumor microenvironment architecture with targeted agents in the multiplex implantable

Juraj Jakubik1,2, Zuzana Tatarova3,4

  • 1German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, a partnership between DKFZ and Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main, Germany.

Signal Transduction and Targeted Therapy
|July 9, 2026
PubMed
Abstract

No abstract available in PubMed .

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The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...