Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Nursing Ethical Principles II01:27

Nursing Ethical Principles II

Ethical principles are essential in guiding nurses to fulfill their responsibilities, focusing on the quality of nursing care and decision-making. These principles, including autonomy, beneficence, non-maleficence, justice, and fidelity, shape the ethical framework within healthcare settings.
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's cancer...
DNA Damage can Stall the Cell Cycle02:36

DNA Damage can Stall the Cell Cycle

In response to DNA damage, cells can pause the cell cycle to assess and repair the breaks. However, the cell must check the DNA at certain critical stages during the cell cycle. If the cell cycle pauses before DNA replication, the cells will contain twice the amount of DNA. On the other hand, if cells arrest after DNA replication but before mitosis, they will contain four times the normal amount of DNA. With a host of specialized proteins at their disposal,cells must use the right protein at...
DNA Damage Can Stall the Cell Cycle02:36

DNA Damage Can Stall the Cell Cycle

In response to DNA damage, cells can pause the cell cycle to assess and repair the breaks. However, the cell must check the DNA at certain critical stages during the cell cycle. If the cell cycle pauses before DNA replication, the cells will contain twice the amount of DNA. On the other hand, if cells arrest after DNA replication but before mitosis, they will contain four times the normal amount of DNA. With a host of specialized proteins at their disposal,cells must use the right protein at...
Nurses' Legal Responsibilities I01:27

Nurses' Legal Responsibilities I

In healthcare, informed consent is a crucial process that involves thoroughly communicating medical treatment options to patients, including benefits, risks, potential side effects, and alternatives. This process enables patients to make well-informed decisions about their care, ensuring they understand the implications of their choices before consenting to or refusing treatment.
The legal responsibilities of a nurse regarding informed consent include the following:
Cancer-Critical Genes II: Tumor Suppressor Genes01:05

Cancer-Critical Genes II: Tumor Suppressor Genes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cancer Education in the Era of Immediate Results Access.

Journal of cancer education : the official journal of the American Association for Cancer Education·2026
Same author

Factors Associated With Digital Health Literacy in the United Kingdom: Cross-Sectional Online Survey.

Journal of medical Internet research·2026
Same author

The trust in AI-generated health advice (TAIGHA) scale and short version (TAIGHA-S): Development and validation study.

PLOS digital health·2026
Same author

What are the perceptions, barriers and opportunities for spatial computing in health and self-care among UK adults? A cross-sectional online survey of the public and healthcare professionals.

BMJ open·2026
Same author

Legitimacy, trust and readiness for implementing lifestyle medicine in England: a cross-sectional study.

BMJ open·2026
Same author

Entrusting Attention: An Additional lens on Entrustable Professional Activity Assessment.

The clinical teacher·2026

Related Experiment Video

Updated: Jul 12, 2026

Working with Human Tissues for Translational Cancer Research
07:48

Working with Human Tissues for Translational Cancer Research

Published on: November 26, 2015

The Paused Pathway: Teaching Investigative Consent when Cancer Investigation Stalls.

Waseem Jerjes1, Sarah Williams2, Austen El-Osta3

  • 1School of Public Health, Faculty of Medicine, Imperial College London, London, UK. waseem.jerjes@nhs.net.

Journal of Cancer Education : the Official Journal of the American Association for Cancer Education
|July 9, 2026
PubMed
Summary

Cancer pathways often pause due to patient barriers. Teaching investigative consent helps patients understand the diagnostic journey, improving cancer communication and care continuity.

Keywords:
Cancer educationInvestigative consentPatient refusalSafety-nettingShared decision-makingSuspected cancer pathway

More Related Videos

Optimization of Breast Biopsy and Mastectomy Sample Collection Procedures for Biobanking, Personalized Medicine, and Research Applications
06:42

Optimization of Breast Biopsy and Mastectomy Sample Collection Procedures for Biobanking, Personalized Medicine, and Research Applications

Published on: September 2, 2025

Related Experiment Videos

Last Updated: Jul 12, 2026

Working with Human Tissues for Translational Cancer Research
07:48

Working with Human Tissues for Translational Cancer Research

Published on: November 26, 2015

Optimization of Breast Biopsy and Mastectomy Sample Collection Procedures for Biobanking, Personalized Medicine, and Research Applications
06:42

Optimization of Breast Biopsy and Mastectomy Sample Collection Procedures for Biobanking, Personalized Medicine, and Research Applications

Published on: September 2, 2025

Area of Science:

  • Oncology
  • Medical Education
  • Patient Communication

Background:

  • Cancer pathways are frequently presented as linear, but patient barriers frequently interrupt this progression.
  • Missed appointments, declined investigations, and misunderstandings can pause the cancer diagnostic journey.
  • Existing approaches may oversimplify patient non-adherence, overlooking complex underlying reasons.

Purpose of the Study:

  • To propose 'investigative consent' as a teachable skill in cancer education.
  • To enhance understanding of the diagnostic journey beyond a single test.
  • To reframe paused cancer pathways as opportunities for learning and improved patient communication.

Main Methods:

  • Conceptual article proposing a new educational skill.
  • Defines investigative consent, encompassing the diagnostic journey, uncertainty, and alternatives.
  • Advocates for a shift in how healthcare professionals interpret and respond to paused pathways.

Main Results:

  • Investigative consent equips patients with a comprehensive understanding of the diagnostic process.
  • It encourages healthcare professionals to explore reasons for pathway pauses beyond simple non-adherence.
  • Emphasizes clarification, patient understanding, and respectful documentation of patient decisions.

Conclusions:

  • Reframing paused cancer pathways as learning events strengthens patient-centered communication.
  • Investigative consent promotes safer continuity of care by addressing patient barriers.
  • This approach fosters a more nuanced and empathetic understanding of the patient experience in cancer diagnosis.