Sodium alginate for wound healing applications: A review

Sodium alginate (SA) is a polysaccharide biopolymer widely used in wound healing applications due to its beneficial role in the hemostatic, inflammatory, and proliferative phases of tissue repair. Its hydrophilic nature supports the wound healing process by enabling efficient absorption of wound exudate and maintaining a moist microenvironment conducive to tissue regeneration. Moreover, SA can form highly porous structures that promote oxygen diffusion and provide a suitable scaffold for neovascularization and new tissue formation. This review summarizes recent advances in the application of SA in wound dressings. A bibliometric analysis of Scopus data using the keywords "sodium alginate" AND "wound healing" reveals a growing number of publications in recent years, highlighting the increasing scientific interest in this field. The expanding utilization of SA in wound healing may be attributed to its favorable properties, including biocompatibility, biodegradability, and low toxicity.