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Modeling of Factors Affecting Hospital Length of Stay in ST-Elevation Patients Using Logistic Regression Models: SEMI

Mohammad Agharazi1, Ehsan Shirvani2, Marjan Jamalian3

  • 1School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Advanced Biomedical Research
|July 10, 2026
PubMed

Insights

Identifying risk factors like high LDL-C, low hemoglobin, and reduced LVEF can shorten ST-elevation myocardial infarction (STEMI) patient length of stay (LOS). This helps reduce healthcare costs and improve recovery for STEMI patients.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Public Health

Background:

  • Ischemic heart disease, including ST-elevation myocardial infarction (STEMI), presents a significant public health challenge.
  • Length of stay (LOS) for STEMI patients directly impacts healthcare costs and resource utilization.
  • Understanding risk factors for prolonged LOS is crucial for optimizing patient care and resource management.

Purpose of the Study:

  • To identify key risk factors associated with extended length of stay (LOS) in ST-elevation myocardial infarction (STEMI) patients.
  • To investigate predictors of prolonged hospitalization among STEMI patients at Chamran Hospital, Isfahan, Iran.
  • To inform strategies for reducing LOS and improving healthcare efficiency for STEMI cases.

Main Methods:

  • Retrospective cohort study of STEMI patients admitted to Chamran Hospital between March 2015 and March 2016.
  • Data collected by trained nurses from medical archives, focusing on patient demographics, medical history, and clinical parameters.
  • Logistic regression analysis employed to determine independent predictors of LOS, with statistical significance set at P < 0.05.

Main Results:

  • Analysis of 760 STEMI patients revealed a median LOS of three days for survivors.
  • Factors associated with longer LOS included older age, female sex, lower left ventricular ejection fraction (LVEF), lower hemoglobin, and a history of cardiovascular diseases.
  • Logistic regression identified higher low-density lipoprotein cholesterol (LDL-C), lower hemoglobin, and lower LVEF as significant risk factors for increased hospitalization duration.

Conclusions:

  • Higher LDL-C, lower hemoglobin, and reduced LVEF are identified as modifiable risk factors impacting STEMI patient LOS.
  • Targeting these factors can potentially shorten hospitalization periods, leading to decreased healthcare expenditure.
  • Effective management of these risk factors is essential for improving patient outcomes and optimizing the use of medical resources in STEMI care.
Abstract

Keywords:
Length of stayST-elevation myocardial infarctionrisk factors

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