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Cryoablation as a downsizing strategy enabling R0 resection in a giant mediastinal desmoid tumor: a case report
Ibtissem Ben Bayer1, Ana Maria Santos Portela1, Dana Mihaela Radu1,2
1Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpitaux Universitaires Paris Seine-Saint-Denis, Hôpital Avicenne, Chirurgie Thoracique et Vasculaire, Université Sorbonne Paris Nord, Faculté de Médecine SMBH, Bobigny, France.
Mediastinum (Hong Kong, China)
|July 10, 2026
Summary
Percutaneous cryoablation (PCA) effectively reduced a giant mediastinal desmoid tumor size, enabling surgical resection in a previously unresectable case. This minimally invasive approach shows promise for multimodal desmoid tumor management.
Area of Science:
- Thoracic oncology
- Minimally invasive surgical techniques
- Soft tissue neoplasia
Background:
- Endothoracic desmoid tumors are rare, locally aggressive neoplasms.
- Intrathoracic location often makes surgical resection challenging.
- Treatment has shifted towards conservative approaches, reserving surgery for select cases.
