Injectable magnetofluids for seamless and personalized cardiac occlusion

Managing long-term embolic risk in atrial fibrillation remains a major clinical challenge, while existing rigid metallic occluders are constrained by anatomical mismatch and persistent risks of device-related thrombus. Recent advances in personalized magnetofluidic systems introduce an in situ liquid-liquid phase separation strategy that enables seamless anatomical conformity and thrombus-free endocardialization, thereby establishing a robust and biocompatible platform for permanent cardiac stroke prevention across diverse left atrial appendage morphologies.