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Updated: Jul 12, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
Renal Recovery Patterns and Long-Term Kidney Function Decline in Pulmonary Hypertension
Lukas Hintz1, Anastasios Stampouloglou1,2, Janani Rangaswami3,4
1Department of Internal Medicine II University Hospital Giessen and Marburg, Justus-Liebig-University Giessen Giessen Hessen Germany.
None:
Pulmonary hypertension (PH) is frequently accompanied by a decline in kidney function. In this retrospective cohort, worsening PH was associated with long-term eGFR decline only when accompanied by transition from acute kidney injury (AKI) to acute kidney disease (AKD), defined as persistent kidney dysfunction beyond 7 days after AKI onset, whereas early AKI reversal was not. These findings suggest that renal recovery patterns, rather than transient changes in kidney function, may determine longitudinal kidney outcomes in PH and warrant further prospective investigation.
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