Optical Performance of a Novel Non-diffractive Presbyopia-Correcting Intraocular Lens as a Function of Defocus and...

To evaluate the optical performance of a novel non-diffractive intraocular lens (IOL) and compare it with established trifocal, extended depth of focus (EDOF), and standard monofocal designs under different pupil apertures and defocus.

Four IOL models were analyzed using a PMTF optical bench (LAMDA-X Ophthalmics): AcrySof IQ (monofocal control; Alcon Laboratories, Inc), Clareon PanOptix (trifocal; Alcon Labratories, Inc), TECNIS PureSee (EDOF; Johnson & Johnson Surgical Vision), and the novel RayOne Galaxy (Rayner Intraocular Lenses, Ltd). Through-focus modulation transfer function (MTF) and point spread function (PSF) were measured across four apertures (2, 3, 3.75, and 4.5 mm). A United States Air Force target was used to assess image reproduction. Halo intensity was quantified by analysis of the PSF tail.

The PanOptix IOL showed three consistent foci across all apertures. The PureSee IOL exhibited high optical quality at distance and extended performance toward intermediate vergences up to 1.75 D as pupil size decreased. The Galaxy IOL demonstrated high optical quality at far focus with large pupils, comparable to the EDOF lens. With smaller pupils, a myopic shift of the main peak (≈0.75 D) enhanced intermediate and near performance. Both the Galaxy and PureSee lenses produced similar halo profiles, with lower intensity than the PanOptix IOL.

The Galaxy IOL exhibits pupil-dependent optical performance, shifting from optimal distance vision with large pupils to improved intermediate and near vision at smaller apertures. The Galaxy and PureSee IOLs induce comparable halo levels, higher than those of monofocal IOLs but lower than those associated with the PanOptix IOL.