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Published on: October 22, 2019
Radiographic Assessment of Alveolar Ridge Preservation Using Controlled-Release of Erythropoietin: A Randomized
Shehad W Saad1, Yasser N El Hadidi2, Doaa Adel-Khattab2
1Faculty of Dentistry, The British University in Egypt, El Shorouk City, Egypt.
Abstract:
The study aimed to evaluate the effect of EPO on ridge resorption. The patients were divided into 3 groups: study group having sockets filled with chitosan (CS)/carbon methyl cellulose (CMC)/gelatin hydrogels loaded with EPO, positive control group having sockets filled with CS/CMC/gelatin hydrogels alone, and control group with natural healing sockets. The average buccal bone height at follow-up was 7.4±1.9 mm compared with 8.4±2.3 mm at baseline with nonsignificant bone loss (P=0.25). Regarding the positive control group, buccal bone height was 7.5±3.3 mm at follow-up compared with 9.4±3.8 mm at baseline, with significant bone loss (P=0.04). Regarding the control group, the average of buccal bone height was 7.7±3 mm at follow-up compared with 9.5±2.8 mm at baseline with significant bone loss (P=0.04). CS loaded-EPO hydrogel reduced ridge resorption compared with spontaneous healing and CS alone.
