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MedTech Innovation: Creating a Startup Company in Orthopaedics.

David M Kalainov¹, Peter McNerney, Jonathan W Gunn

¹From the Department of Orthopaedic Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, and the Northwestern University Farley Center for Entrepreneurship and Innovation, Evanston, IL (Kalainov), the Northwestern University Kellogg School of Management, Evanston, IL (McNerney), and the Northwestern University Pritzker School of Law, Chicago, IL (Gunn).

The Journal of the American Academy of Orthopaedic Surgeons

|July 10, 2026

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The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
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Orthopaedic surgeons can innovate musculoskeletal health solutions. This study provides a roadmap for medical technology (MedTech) startups, addressing common challenges and increasing the likelihood of success in bringing new devices to market.

Area of Science:

Orthopaedic surgery and medical technology (MedTech) innovation.

Background:

Orthopaedic surgeons identify unmet musculoskeletal health needs but lack formal innovation training.
The medical device startup landscape is complex, with high failure rates (up to 90%) due to various challenges.

Purpose of the Study:

To provide a roadmap for orthopaedic surgeons and innovators in the MedTech sector.
To guide the development and marketing of solutions for unmet musculoskeletal health needs.
To build upon existing research on innovation in orthopaedic surgery.

Main Methods:

The study synthesizes knowledge on the MedTech startup process.
It draws from a previous publication in the Journal of the American Academy of Orthopaedic Surgeons.
The approach focuses on creating a practical guide for innovators.

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Main Results:

A roadmap is presented to navigate the complexities of MedTech innovation.
Key challenges faced by medical device and software startups are addressed.
Strategies are outlined to improve the success rate of bringing new musculoskeletal health solutions to market.

Conclusions:

Understanding the MedTech startup process is crucial for orthopaedic surgeons.
This roadmap can aid innovators in successfully marketing musculoskeletal health solutions.
Enhanced knowledge of innovation can help surgeons evaluate new devices effectively.