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Published on: June 10, 2025
Health Care Use and Outcomes in Heart Failure: Are There Lingering Impacts From the COVID-19 Pandemic?
Finlay A McAlister1, Chuan Wen2, Jeffrey A Bakal2
1Department of Medicine, University of Alberta, Edmonton, Alberta, Canada; Canadian VIGOUR Centre, University of Alberta, Edmonton, Alberta, Canada; Alberta Strategy for Patient Oriented Research Unit (AbSPORU), Edmonton, Alberta, Canada.
Insights
Post-COVID-19, heart failure (HF) patients experienced fewer hospitalizations and emergency department (ED) visits, with increased presentation severity. Non-COVID mortality rates remained consistent with pre-pandemic trends.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- The long-term effects of the COVID-19 pandemic on heart failure (HF) patient care remain unclear.
- Understanding these impacts is crucial for optimizing future healthcare strategies.
Purpose of the Study:
- To investigate changes in healthcare utilization and outcomes for patients with heart failure (HF) from March 2018 to May 2024.
- To assess residual impacts of the COVID-19 pandemic on HF patient management and outcomes.
Main Methods:
- A retrospective cohort study utilizing interrupted time series (ITS) analysis.
- Compared monthly rates of mortality, hospitalizations, and emergency department (ED) visits for HF patients across pre-pandemic, intra-pandemic, and post-pandemic periods.
- Adjusted for demographic factors, comorbidities, seasonality, and pre-pandemic trends.
Main Results:
- Patients with HF had more severe presentations (higher Canadian Triage Acuity Scores) during and after the pandemic.
- All-cause hospitalizations and ED visits significantly decreased during and post-pandemic compared to pre-pandemic.
- Non-COVID mortality rates declined post-pandemic, but this trend was consistent with pre-pandemic patterns.
Conclusions:
- The reduction in hospitalizations and ED visits for HF patients persisted beyond the pandemic.
- Increased severity of patient presentation was observed during and after the pandemic.
- The observed decrease in non-COVID mortality aligns with pre-pandemic trends, suggesting no significant residual impact on this outcome.
Background:
Whether there are residual impacts after the COVID-19 pandemic for patients with heart failure (HF) is unknown.
Objectives:
To explore HF-related health care use and outcomes between March 2018 and May 2024.
Methods:
Retrospective cohort study using interrupted time series (ITS) to compare monthly rates of mortality, hospitalizations, emergency department (ED) visits, and ambulatory care visits in patients with HF pre-pandemic (March 12, 2018-March 11, 2020), intra-pandemic (March 12, 2020-May 11, 2023), and post-pandemic (May 12, 2023-May 11, 2024), adjusted for age, sex, socioeconomic status, comorbidity burden, seasonality, and pre-pandemic trends.
Results:
Although demographics and comorbidities were similar across all 3 periods (66,782 patients pre-pandemic, 77,473 intra-pandemic, and 82,072 post-pandemic), patients with HF presenting to an ED or being hospitalized had more severe Canadian Triage Acuity Scores during and post-pandemic than pre-pandemic (both P < 0.001). Over a median follow-up time of 2.9 years (IQR: 1.1-5.9 years), monthly outcomes were significantly lower during and post-pandemic for all-cause hospitalizations (incidence rate ratio: 0.83 [95% CI: 0.81-0.86] and 0.81 [0.78-0.84]), and all-cause ED visits (0.81 [0.78-0.84] and 0.84 [0.80-0.89]), even after adjusting for covariates and pre-pandemic trends (ITS P = 0.001, and 0.005, respectively). Non-COVID mortality rates were lower post-pandemic (incidence rate ratio 0.58 [0.53-0.63]) but ITS analysis revealed this was not a significant departure from pre-pandemic trends (P = 0.79).
Conclusions:
The declines in hospitalizations and ED visits seen during the pandemic continued post-pandemic, severity of presentation increased, and the decline in non-COVID mortality rates was consistent with pre-pandemic trends.
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