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Related Concept Videos

Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
Heart Failure VII: Nursing Interventions01:30

Heart Failure VII: Nursing Interventions

The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
Heart Failure IV: Classification and Diagnostic Evaluation01:30

Heart Failure IV: Classification and Diagnostic Evaluation

Heart failure can be classified in various ways, with the most common classifications based on physical activity limitations, disease progression, severity, and treatment strategies.The Functional Classification of Heart Failure divides patients into four categories based on physical activity limitation due to symptom burden.Class I: Patients in this class have cardiac disease but no physical activity limitations. Ordinary activities like walking, climbing stairs, or routine tasks do not cause...
Heart Failure Drugs: β-Blockers01:22

Heart Failure Drugs: β-Blockers

β-adrenergic antagonists, commonly known as β-blockers, block the effects of sympathetic neurotransmitters such as noradrenaline (NA) and adrenaline (ADR). They have several beneficial effects in heart failure treatment. They reduce heart rate, the force of contraction, and cardiac muscle relaxation. They also slow the atrial-ventricular conduction rate and raise the threshold for arrhythmias. The concentration of β-blockers determines their effects on bronchodilation, vasodilation, and...

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Related Experiment Video

Updated: Jul 12, 2026

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models
07:49

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models

Published on: July 21, 2023

SLEEP-DISORDERED BREATHING IN HEART FAILURE: PHENOTYPES, MECHANISMS, AND PRECISION APPROACH.

Huijie Yi1, Luciano F Drager2, Xiao Wang3

  • 1Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Respiratory and Sleep Medicine, Peking University People's Hospital, Beijing, China.

Journal of Cardiac Failure
|July 10, 2026
PubMed
Summary

Sleep-disordered breathing (SDB) is common in heart failure (HF) but treatments like CPAP lack proven mortality benefits. Personalized approaches using physiological markers are needed for better SDB management in HF patients.

Keywords:
CARDIOVASCULAR OUTCOMESCENTRAL SLEEP APNEACONTINUOUS POSITIVE AIRWAY PRESSURE (CPAP)HEART FAILUREOBSTRUCTIVE SLEEP APNEASLEEP DISORDERED BREATHING

More Related Videos

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
09:20

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction

Published on: February 13, 2021

Related Experiment Videos

Last Updated: Jul 12, 2026

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models
07:49

A Pacing-Controlled Procedure for the Assessment of Heart Rate-Dependent Diastolic Functions in Murine Heart Failure Models

Published on: July 21, 2023

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
09:20

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction

Published on: February 13, 2021

Area of Science:

  • Cardiology
  • Pulmonology
  • Sleep Medicine

Background:

  • Sleep-disordered breathing (SDB), including obstructive sleep apnea (OSA) and central sleep apnea (CSA), is prevalent in heart failure (HF).
  • SDB is linked to adverse cardiac remodeling, arrhythmias, and poor clinical outcomes in HF patients.
  • Current SDB treatments in HF show limited success in reducing mortality or hospitalizations despite improving some physiological markers.

Purpose of the Study:

  • To review the current understanding of SDB in HF.
  • To evaluate the effectiveness of existing and emerging SDB therapies in HF.
  • To advocate for precision-based, phenotype-specific management strategies for SDB in HF.

Main Methods:

  • Review of existing literature on SDB in HF.
  • Analysis of clinical trial data for CPAP, adaptive servo-ventilation, and alternative therapies.
  • Evaluation of novel physiological markers for risk stratification.

Main Results:

  • Continuous positive airway pressure (CPAP) improves symptoms and oxygenation in OSA but has not demonstrated reduced mortality in HF.
  • Adaptive servo-ventilation shows neutral or adverse long-term outcomes in CSA, suggesting it may be a marker of HF severity.
  • Novel markers like hypoxic burden and autonomic responses may better predict treatment response than traditional metrics.

Conclusions:

  • Conventional SDB treatments lack consistent mortality benefits in HF.
  • Central sleep apnea in HF may be a marker of disease severity rather than a direct therapeutic target.
  • A phenotype-specific, precision-based approach integrating HF characteristics and physiological markers is crucial for optimizing SDB management in heart failure.