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Updated: Jul 12, 2026
A Real-World High-Intensity Interval Training Protocol for Cardiorespiratory Fitness Improvement
Published on: February 22, 2022
High-intensity interval training improves myocardial work and cardiac function in women with obesity: a randomized
Caroline Ferraz Simões1,2, Higor Barbosa Reck1,3, João Carlos Locatelli4
1Research Group on Systemic Arterial Hypertension, Arterial Stiffness and Vascular Aging, Maringa, Brazil.
None:
The purpose of this study was to investigate the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on cardiac function and myocardial work (MW) in women with obesity. Twenty-five women with obesity (Age: 28 ± 5 years, BMI: 35.03 ± 3.19 kg/m²) were randomized to 8 weeks of either HIIT (n = 11, 4×4-min at 85-95% of HRmax) or MICT (n = 14, 41-min at 65-75% of HRmax). Cardiac function and strains were evaluated using two-dimensional speckle tracking echocardiography. MW indices were computed via dedicated software. HIIT significantly improved myocardial efficiency, as evidenced by a reduction in global wasted work (GWW [d = 0.64, p = 0.042]) and an increase global work efficiency (GWE [d = 0.83, p = 0.005]). Both HIIT and MICT reduced left ventricular global longitudinal strain (GLS, p = 0.017 for HIIT; p = 0.023 for MICT), left atrial (LA) contraction (p < 0.001 for both), LA conduit (p = 0.002 for both), LA reservoir (p = 0.003 for HIIT; p < 0.001 for MICT), and LA stiffness (p = 0.004 for HIIT, p = 0.031 for MICT). HIIT and MICT both improved myocardial deformation in women with obesity. However, only HIIT improved myocardial efficiency, suggesting a potential superiority for targeting subclinical cardiac dysfunction in this population.
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