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Published on: August 15, 2025
Unique Imaging Findings of a Calvarial Ossifying Fibroma Successfully Managed With Surgery and Definitive Intent
Andrea Mosca1,2, Melanie Dobromylskyj3, Ivan Doran2
1Veterinary Specialty Hospital (VSH) Hong Kong, Wan Chai, Hong Kong, Hong Kong.
Summary
A Boxer dog with calvarial ossifying fibroma experienced periocular swelling and nasal issues. Surgical excision and radiotherapy led to durable local control, with no recurrence observed after one year.
Area of Science:
- Veterinary Medicine
- Oncology
- Neurosurgery
Background:
- Ossifying fibroma is a rare benign bone tumor.
- Calvarial and sinonasal involvement can cause significant clinical signs.
Purpose of the Study:
- To describe a case of calvarial ossifying fibroma in a dog.
- To detail the diagnostic and therapeutic approach.
- To report the long-term outcome.
Main Methods:
- Computed tomography (CT) for serial imaging.
- Ultrasound-guided needle aspiration and surgical biopsy.
- CT-guided core biopsy for histopathology.
- Partial surgical excision followed by volumetric modulated arc radiotherapy (VMAT).
Main Results:
- A 6-year-old Boxer dog presented with periocular swelling, nasal discharge, epistaxis, and exophthalmos.
- CT revealed an expansile calvarial lesion and a sinonasal mass with turbinate destruction.
- Histopathology confirmed ossifying fibroma.
- VMAT achieved durable local control with no recurrence >1 year post-treatment.
Conclusions:
- Calvarial ossifying fibroma can present with complex clinical signs in dogs.
- A multimodal approach including surgery and radiotherapy can achieve long-term disease control.
- Long-term ophthalmological monitoring and medication are necessary post-treatment.

