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Burden and risk of elderly atopic dermatitis in Europe: A 2021 global burden of disease analysis
Zhengyang Zhou1, Hongxing Wang2, Bin Yang1
1Department of Dermatology, Dermatology Hospital, Southern Medical University, Guangzhou, Guangdong, China; The First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China.
Background:
The burden of atopic dermatitis (AD) in elderly is increasing recently, so it is necessary to deepen the recognition.
Methods:
We extracted prevalence, incidence and disability-adjusted life years (DALYs) for elderly-AD in Europe used Global Burden of Disease (GBD) and analyzed its related factors.
Results:
The burden of elderly-AD in Europe increased significantly from 1990 to 2021 (changed prevalence: 2.09%; changed DALYs: 11.58%) and females are higher than males. From the perspective of regional heterogeneity, the burden of elderly-AD in Western Europe is much heavier than other areas. Socio-demographic index (r = 0.497, P < 0.001), high alcohol use (r = 0.50, P < 0.001) and high red meat diet (r = 0.46, P < 0.001) are positively related to the incidence of elderly-AD, while low nuts and seeds intake (r = -0.50, P < 0.001), low seafood omega-3 fatty acids diet (r = -0.74, P < 0.001), low omega-6 polyunsaturated fatty acids diet (r = -0.43, P < 0.001) and high sodium diet (r = -0.62, P < 0.001) are negatively related to the incidence rate of elderly-AD.
Conclusion:
The burden of elderly-AD is relatively high level in Europe with regional and gender disparities, and dietary habits are probably contributor.
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