Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biofilms01:29

Biofilms

Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
Bioavailability Enhancement: Drug Stability Enhancement and GI Retention01:05

Bioavailability Enhancement: Drug Stability Enhancement and GI Retention

Improving a drug's stability in the gastrointestinal (GI) tract is paramount for enhancing its bioavailability and therapeutic effectiveness. Various strategies are employed to protect the drug from the harsh gastric milieu and to ensure its release and absorption at the desired site within the GI tract.Polymer coatings are one such method used to shield drugs from the stomach's acidic environment. By preventing premature drug release, these coatings improve the bioavailability of unstable...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of the quality of life of individuals with head and neck cancer undergoing surgery and radiotherapy.

Brazilian oral research·2026
Same author

Effects of phytic and tannic acids on dentin bonding, nanoleakage, and micropermeability under wet and dry bonding techniques.

Odontology·2026
Same author

Preemptive photobiomodulation therapy for reducing pain during local anesthetic needle puncture in dental and craniomaxillofacial procedures: a systematic review and meta-analysis of randomized clinical trials.

Journal of dentistry·2026
Same author

Imbalances in the immunostaining of TLR2 and TLR4, and their respective second messengers, impair the prognosis of oral squamous cell carcinoma.

Oral surgery, oral medicine, oral pathology and oral radiology·2026
Same author

Corticoids Reduce Incidence of Oral Mucositis during Antineoplastic Treatment? A Systematic Review and Meta-Analysis of Randomized and Nonrandomized Clinical Trials.

Asian Pacific journal of cancer prevention : APJCP·2026
Same author

Alogliptin Delays the Healing of Traumatic Oral Ulcers in the Buccal Mucosa of Wistar Rats.

Fundamental & clinical pharmacology·2026

Related Experiment Video

Updated: Jul 12, 2026

Confocal Time Lapse Imaging as an Efficient Method for the Cytocompatibility Evaluation of Dental Composites
07:04

Confocal Time Lapse Imaging as an Efficient Method for the Cytocompatibility Evaluation of Dental Composites

Published on: November 9, 2014

Are flowable composite resins containing bioactive particles truly biocompatible?

Lara Rabelo Aragão1, Julia Gonçalves Montenegro2, Clarice Lioba de Araújo2

  • 1Master in Dental Sciences, University Christus, Fortaleza, Ceará, Brazil.

Journal of Clinical and Experimental Dentistry
|July 11, 2026
PubMed
Summary

Flowable bioactive composite resins showed minimal tissue inflammation and high conversion rates in dental applications. These materials are promising alternatives for dental practice due to their biocompatibility and effectiveness.

More Related Videos

Roughness Impact of Piezoelectric Dental Scaler on Two Distinct Flowable Composite Filling Materials
05:30

Roughness Impact of Piezoelectric Dental Scaler on Two Distinct Flowable Composite Filling Materials

Published on: January 10, 2025

Biological Compatibility Profile on Biomaterials for Bone Regeneration
10:28

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

Related Experiment Videos

Last Updated: Jul 12, 2026

Confocal Time Lapse Imaging as an Efficient Method for the Cytocompatibility Evaluation of Dental Composites
07:04

Confocal Time Lapse Imaging as an Efficient Method for the Cytocompatibility Evaluation of Dental Composites

Published on: November 9, 2014

Roughness Impact of Piezoelectric Dental Scaler on Two Distinct Flowable Composite Filling Materials
05:30

Roughness Impact of Piezoelectric Dental Scaler on Two Distinct Flowable Composite Filling Materials

Published on: January 10, 2025

Biological Compatibility Profile on Biomaterials for Bone Regeneration
10:28

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

Area of Science:

  • Biomaterials Science
  • Dental Materials
  • Nanotechnology

Background:

  • Flowable composite resins are widely used in restorative dentistry.
  • Bioactive particles incorporated into dental composites aim to enhance their properties.
  • Evaluating the conversion and biocompatibility of these advanced materials is crucial.

Purpose of the Study:

  • To assess the degree of conversion (DC) of flowable composite resins with bioactive particles.
  • To evaluate the in vivo biocompatibility (BC) of these resins using a rat model.
  • To compare the performance of Beautifil Flow Plus F00, Beautifil Flow Plus F03, and Filtek Supreme.

Main Methods:

  • Raman spectroscopy was used to determine the degree of conversion.
  • Subcutaneous implantation in Wistar rats was performed for biocompatibility testing over 28 days.
  • Histological analysis of tissue response, including inflammation and fibrosis, was conducted.

Main Results:

  • No statistically significant difference in the degree of conversion was found among the tested composite resins.
  • Resins Beautifil Flow Plus F00 and F03 demonstrated reduced inflammation and granulation tissue formation compared to Filtek Supreme.
  • Greater fibrosis was observed with Beautifil Flow Plus F00 and F03, indicating a favorable host response.

Conclusions:

  • Flowable bioactive composite resins exhibit promising biocompatibility, with lower inflammatory responses.
  • High conversion rates were achieved, ensuring material integrity.
  • These bioactive resins are suitable alternatives for dental restorative procedures.