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Updated: Jul 12, 2026
11:49
Surgical Induction of Endolymphatic Hydrops by Obliteration of the Endolymphatic Duct
Published on: January 22, 2010
Endolymphatic hydrops in patients with migraine: a correlative study
Anne R J Péporté1, Fabian Schön2, Gustav Andreisek2,3
1Department of Radiology, Cantonal Hospital Frauenfeld, Frauenfeld, Switzerland.
Frontiers in Neurology
|July 11, 2026
Summary
Endolymphatic hydrops (EH) severity did not correlate with migraine brain biomarkers on MRI scans. These findings suggest EH and migraine-related brain changes are distinct imaging phenomena.
Area of Science:
- Neurology
- Radiology
- Otolaryngology
Background:
- Endolymphatic hydrops (EH) is the pathological hallmark of Menière's disease (MD).
- Delayed phase 3 Tesla MRI is used to visualize EH.
- Migraine is associated with specific brain imaging biomarkers.
Purpose of the Study:
- To investigate the correlation between the severity of endolymphatic hydrops (EH) and established migraine brain biomarkers using MRI.
- To explore potential associations between EH and cranial nerve volumes in patients.
Main Methods:
- Retrospective review of 108 inner ear MRIs from 144 scans.
- Two blinded radiologists graded EH severity and assessed migraine markers (WML, enlarged perivascular spaces).
- Binary logistic regression analysis was used to determine associations.
Main Results:
- No significant associations were found between EH severity and migraine biomarkers or cranial nerve volumes (p > 0.05).
- Grade 2 vestibular and cochlear EH were predominant.
- A weak association was noted between grade 1 left vestibular EH and sudden hearing loss, and grade 1 left cochlear EH and aural fullness.
Conclusions:
- Endolymphatic hydrops severity is not associated with migraine-related MRI biomarkers.
- EH and migraine-associated structural brain changes may be distinct imaging findings.
- Further research is needed to understand the relationship between inner ear disorders and neurological conditions.
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