Related Experiment Video

Updated: Jul 12, 2026

Cryopreservation of Mouse Embryos by Ethylene Glycol-Based Vitrification
06:00

Cryopreservation of Mouse Embryos by Ethylene Glycol-Based Vitrification

Published on: November 18, 2011

Retraction: Cryopreservation: A Review Article.

Anurag N Jaiswal1, Anjali Vagga2

  • 1Medical Education, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.

Cureus
|July 11, 2026
PubMed
Summary

This article has been retracted. The retraction notice indicates that the original study, identified by DOI: 10.7759/cureus.31564, is no longer considered valid.

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Conventional electron microscopy (EM) involves dehydration, fixation, and staining of biological samples, which distorts the native state of biological molecules and results in several artifacts. Also, the high-energy electron beam damages the sample and makes it difficult to obtain high-resolution images. These issues can be addressed using cryo-EM, which uses frozen samples and gentler electron beams. The technique was developed by Jacques Dubochet, Joachim Frank, and Richard Henderson, for...