Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Factors Affecting Renal Clearance: Renal Impairment01:17

Factors Affecting Renal Clearance: Renal Impairment

Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
Physiology of the Genitourinary System I: Renal Blood Flow and Glomerular Filtration01:29

Physiology of the Genitourinary System I: Renal Blood Flow and Glomerular Filtration

The kidneys are vital organs responsible for regulating blood filtration, waste excretion, and fluid balance, all of which are crucial for maintaining homeostasis. Renal physiology examines renal blood flow, glomerular filtration, and urine formation, ensuring the body’s internal environment remains stable.Renal Blood FlowThe kidneys receive about 20-25% of the cardiac output, typically around 1200 mL of blood per minute in an average adult. Blood flows into the kidneys through the renal...
Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of fluid...
Physiology of the Genitourinary System III: Urine Concentration and Dilution01:20

Physiology of the Genitourinary System III: Urine Concentration and Dilution

The kidneys concentrate or dilute urine to maintain water and electrolyte balance. Nephrons, particularly the loop of Henle, play a crucial role in this process through the countercurrent multiplication system. This system establishes a high osmolarity in the renal medulla, which is essential for water reabsorption. In the loop of Henle’s descending limb, water is reabsorbed into the surrounding medulla due to its permeability to water. In contrast, the ascending limb actively transports...
Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration01:28

Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration

Glomerular filtration rate (GFR) can be estimated from serum creatinine using the modification of diet in renal disease (MDRD) formula or the chronic kidney disease–epidemiology collaboration (CKD–EPI) equation. Both methods are widely used in clinical practice to assess kidney function and guide treatment decisions.The MDRD equation does not require weight or height measurements and is normalized to the body surface area of 1.73 m², considered the average adult surface area. This equation is...
Renal Drug Clearance: Overview01:06

Renal Drug Clearance: Overview

Renal clearance is a crucial parameter in pharmacokinetics that quantifies the rate at which the kidneys excrete a drug. It represents a constant fraction of the central volume of distribution containing the drug that the kidney eliminates per unit of time.
Renal clearance can be calculated using different methods. One approach is to divide the urinary drug excretion rate by the plasma drug concentration. This method directly measures renal clearance, indicating the kidneys' efficiency in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Overlap Syndromes and Associated Immunoglobulin-G4-Related Liver Diseases.

Journal of clinical and experimental hepatology·2026
Same author

Circadian profile of 24-hour ambulatory blood pressure monitoring in healthy young adults.

The National medical journal of India·2026
Same author

Artificial intelligence-based automated sleep staging using heart rate variability: Assessment of performance and clinical prospects.

The National medical journal of India·2026
Same author

Bacosine triggers NRF2-TFEB-autophagy axis to attenuate arecoline-induced oxidative stress and inflammasome activation.

Toxicology in vitro : an international journal published in association with BIBRA·2026
Same author

Adaptive-Lag approach for assessing baroreflex functions: validation with the eurobavar dataset.

Journal of human hypertension·2026
Same author

Frequency and predictors of fructose malabsorption in patients with functional abdominal pain syndrome: A case-control study.

World journal of gastrointestinal pathophysiology·2026

Related Experiment Video

Updated: Jul 12, 2026

Physiology Lab Demonstration: Glomerular Filtration Rate in a Rat
06:58

Physiology Lab Demonstration: Glomerular Filtration Rate in a Rat

Published on: July 26, 2015

Effectiveness of a Numerical Problem-Solving Module in Enhancing Renal Physiology Comprehension.

Mayank Agarwal1, Manish Goyal2, Priyadarshini Mishra2

  • 1Physiology, All India Institute of Medical Sciences, Raebareli, Raebareli, IND.

Cureus
|July 11, 2026
PubMed
Summary
This summary is machine-generated.

A new numerical problem-solving module significantly improved first-year medical students' understanding of renal physiology. This approach particularly benefited lower-achieving students, enhancing their analytical skills and confidence in the subject.

Keywords:
competency-based educationmedical educationnumerical analysisrenal physiologyteaching methods

More Related Videos

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

Related Experiment Videos

Last Updated: Jul 12, 2026

Physiology Lab Demonstration: Glomerular Filtration Rate in a Rat
06:58

Physiology Lab Demonstration: Glomerular Filtration Rate in a Rat

Published on: July 26, 2015

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

Area of Science:

  • Medical Education
  • Physiology
  • Quantitative Skills

Background:

  • Renal physiology presents significant challenges for medical students due to its complex and quantitative nature.
  • Traditional teaching methods often fall short in fostering deep conceptual understanding and analytical reasoning.
  • Competency-based medical education necessitates innovative pedagogical approaches in India.

Purpose of the Study:

  • To evaluate the effectiveness of a numerical problem-solving module in improving first-year medical students' comprehension of renal physiology.
  • To assess the impact of this module on conceptual understanding and analytical skills.

Main Methods:

  • A quasi-experimental, pre- and post-test intervention study was conducted with first-professional medical students.
  • The intervention involved small-group discussions of a 20-question renal physiology numerical problem-solving module following lectures.
  • Assessments included 17 multiple-choice questions (MCQs) administered via Google Forms, alongside a validated questionnaire for student perceptions.

Main Results:

  • Post-test scores showed a statistically significant improvement compared to pre-test scores (p < 0.001).
  • Students who initially scored lower on the pre-test demonstrated the most significant improvement in post-test scores (p < 0.001).
  • Student feedback overwhelmingly supported the module, citing increased engagement, deeper understanding, and improved peer collaboration.

Conclusions:

  • The numerical problem-solving module effectively enhanced students' understanding of renal physiology.
  • This intervention particularly benefited lower-achieving students, boosting their analytical abilities and confidence.
  • Numerical problem-solving modules show promise as a valuable addition to medical curricula for developing critical thinking skills.