An exploratory evaluation of the therapeutic potential of Parmentiera aculeata
Araceli Guerrero-Alonso1, María C Columba-Palomares2, Yomara Malitzin Martínez-Mercado2
1Chemical Research Center-IICBA, Autonomous University of the State of Morelos, Cuernavaca, Mexico.
Abstract:
The chemical composition of Parmentiera aculeata extracts was analysed by GC-MS and NMR. Two extracts were prepared by maceration at room temperature: a fruit extract (PA-F) and a leaf extract (PA-L). The PA-F extract showed the highest antioxidant activity and phenolic content, whereas the PA-L extract exhibited the strongest antimicrobial activity, particularly against Streptococcus pyogenes. In addition, both extracts reduced 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ear edoema in a murine model by approximately 20%. These findings highlight P. aculeata as a promising source of bioactive compounds with therapeutic potential.
