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Updated: Jul 13, 2026
04:24
A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program
Published on: April 19, 2019
NOTIFY-HF: A Randomized Pilot Trial of Patient-Facing Alerts for Worsening Heart Failure Using Multiparameter
Joseph Assad1, Nancy E Briggs2, Sidney Lo3
1Department of Cardiology, Liverpool Hospital, South Western Sydney Local Health District, Sydney, New South Wales, Australia; South West Clinical School, School of Clinical Medicine, University of New South Wales, Sydney, New South Wales, Australia; Ingham Institute of Applied Medical Research, Liverpool, New South Wales, Australia.
JACC. Heart Failure
|July 11, 2026
Summary
A patient-facing mobile health tool using HeartLogic alerts proved feasible and acceptable for heart failure management. This approach reduced alert burden, suggesting potential for wider clinical use.
Area of Science:
- Cardiology
- Digital Health
- Medical Informatics
Background:
- Worsening heart failure (HF) often follows gradual physiological decline, but current remote monitoring alerts are clinician-focused, delaying action.
- A patient-centered approach is needed to empower individuals in managing their HF and responding to early warning signs.
Purpose of the Study:
- To assess the feasibility and acceptability of a patient-facing HeartLogic-guided mobile health (mHealth) pathway for early HF deterioration detection.
- To explore clinical associations of this novel mHealth intervention in a pilot randomized trial.
Main Methods:
- A single-center, pragmatic randomized pilot trial involving 160 adults with HF and HeartLogic-capable implantable cardioverter-defibrillators.
- Participants were randomized 1:1 to usual care or usual care plus a patient-facing mHealth pathway with HeartLogic-triggered notifications, symptom screening, and self-care guidance.
- Coprimary outcomes included feasibility, acceptability (via Mobile App Usability Questionnaire), and HeartLogic recovery metrics over 12-24 months.
Main Results:
- The intervention demonstrated high feasibility and acceptability, with 80% symptom-screen completion during alerts and high retention rates.
- Compared to usual care, the mHealth pathway significantly lowered HeartLogic alert incidence (IRR: 0.78) and increased monitored days outside alert states (RR: 1.13).
- The risk-tiered pathway facilitated appropriate patient response, with greater healthcare contact following higher-risk alerts.
Conclusions:
- A patient-facing HeartLogic-guided mHealth pathway is feasible and acceptable for managing heart failure.
- The intervention effectively reduced the alert burden in patients with HF.
- Findings support further evaluation of this mHealth approach in larger, multicenter trials.
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