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Updated: Jul 13, 2026
08:56
Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
Published on: October 7, 2021
A Practical Guide to Management of Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Johannes Jakobsen1,2, Chafic Karam3, Krista Kuitwaard4,5
1Department of Neurology, Copenhagen Neuromuscular Center, Section 8077, University of Copenhagen, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark. johannes.klitgaard.jakobsen@gmail.com.
Neurology and Therapy
|July 11, 2026
Summary
Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an autoimmune neuropathy. This review offers insights into CIDP treatment, emphasizing personalized management based on regional resources and patient response.
Area of Science:
- Neurology
- Immunology
- Peripheral Nerve Disorders
Background:
- Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is the most common immune-mediated peripheral neuropathy.
- It presents with progressive muscle weakness, areflexia, and sensory loss, driven by autoimmune processes.
- Current treatments include intravenous immunoglobulin, corticosteroids, and plasma exchange.
Purpose of the Study:
- To provide insights into CIDP treatment considerations.
- To highlight the importance of regional resources and professional experience in managing CIDP.
- To guide physicians in adjusting, withdrawing, or switching treatments based on patient response.
Main Methods:
- Review of the 2021 international CIDP guideline.
- Incorporation of regional treatment frameworks from EU and US.
- Utilization of expert experience from physicians managing CIDP.
- Analysis of example cases to illustrate treatment decisions.
Main Results:
- CIDP treatment response is variable due to disease heterogeneity.
- Regional factors, like immunoglobulin availability, influence treatment choices.
- Reconsidering diagnosis is crucial for patients with poor treatment response.
Conclusions:
- Personalized treatment strategies are essential for effective CIDP management.
- Monitoring treatment response and adapting therapy are key to patient benefit.
- This article serves as a resource for professionals managing CIDP, emphasizing practical considerations.
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