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Updated: Jul 13, 2026

Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury
Published on: June 21, 2019
Contralateral interictal epileptiform discharges in acute stroke: When the unaffected hemisphere matters
Paolo Manganotti1, Edoardo Ricci1, Giovanni Furlanis1
1Clinical Unit of Neurology, Department of Medicine, Surgery and Health Sciences, University Hospital and Health Services of Trieste, University of Trieste, Friuli-Venezia Giulia, Italy.
Objective:
This study aimed to assess the prevalence and predictive factors of contralateral-interictal epileptiform discharges (c-IEDs) in patients with acute stroke (AS) using point-of-care EEG within the first 72 h of admission.
Methods:
We retrospectively analyzed the data of AS patients who underwent point-of-care EEG within 72 h of admission between September 2020 and May 2023 of a single-center Stroke Unit. A multivariate logistic regression model identified variables associated with the onset of c-IEDs.
Results:
Among 647 patients, 148 (22.9%) exhibited IEDs on EEG within 72 h of admission. Of these, 21 patients (14.2%) showed exclusively contralateral IEDs, while 127 patients (85.8%) exhibited ipsilateral IEDs, including 28 (18.9%) with contralateral spread. Independent predictors of c-IEDs occurrence included NIHSS at admission (p = 0.012), stroke lesion volume (p = 0.048) and C-reactive protein levels (p = 0.009).
Conclusion:
This study highlights the pivotal role of early point-of-care EEG in detecting c-IEDs in patients with AS, observed in 3.25% of the cohort. Higher NIHSS scores at admission, larger stroke lesion volumes, and elevated CRP levels were identified as independent predictors of c-IEDs.
Significance:
These findings suggest that the identification of c-IEDs may serve as an additional marker of stroke severity.
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