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Intramedullary osteosclerosis of the tibia with inflammatory features: Multimodality imaging findings

Juan Felipe Betancur1, Melina González Diaz-Granados2, Sergio Andrés Arroyave3

  • 1Leader of the Internal Medicine Investigation Unit, Centro de Investigaciones clínicas SURA, Medellín, Colombia.

Radiology Case Reports
|July 12, 2026
PubMed
Summary

Intramedullary osteosclerosis, a rare bone disorder, can present with unusual inflammatory imaging features like bone marrow edema. Recognizing this spectrum is key to accurate diagnosis and avoiding misidentification as infection or tumors.

Keywords:
Bone marrow edemaCortical thickeningDiaphyseal sclerosisIntramedullary osteosclerosisPeriosteal reactionRibbing disease

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The tibia is the main weight-bearing bone of the lower leg. It is larger than the fibula with which it is paired. The tibia is also the second longest bone in the body and is located right below the skin. The proximal end of the tibia forms the medial and the lateral condyle, which articulates with the condyles of the femur to form the knee joint. Between the articulating surfaces is the irregular elevated area known as the intercondylar eminence that serves as the inferior attachment point for...