Related Experiment Videos
The relationship between social parameters and life satisfaction and functional outcomes: a systematic review and
Chuxi Pan1,2, Urooba Shaikh2, Thaisa Tylinski Sant'Ana2
1Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Purpose:
Association between social determinants of health (SDoH) and functional outcomes and life satisfaction after traumatic brain injury (TBI) has not been systematically analyzed, constituting a knowledge gap.
Material And Methods:
We searched six databases on August 15, 2025, for observational studies reporting associations between SDoH and functional outcomes or life satisfaction. We applied PROGRESS-Plus framework to analyze data. We conducted meta-analysis and visualized results for certainty assessment.
Results:
We included 31 studies of excellent and good quality involving 101,239 adults with TBI (85% male/men, mean age 38.8 ± 17.1 years). Education, social capital, and occupation were the most commonly examined SDoH. Meta-analysis revealed significant gender/sex differences in the Functional Independence Measure (FIM) Total, Cognitive, and Motor scores (standardized mean difference, SMD 0.13 [0.09, 0.16]; -0.16 [-0.32, -0.01]; 0.20 [0.07. 0.33], respectively); and Glasgow Outcome Scale Extended (GOS-E) scores (SMD 0.35 [0.05, 0.66]). No significant gender/sex effect was observed for life satisfaction (SMD 0.23 [-0.09, 0.55]). Moderate certainty suggests links between race/ethnicity and social capital with GOS/GOS-E; and education and age with employment. All other findings were low or very low in certainty.
Conclusion:
Evidence on SDoH is essential for advancing our understanding of functional outcomes and life satisfaction after TBI. PROSPERO: CRD42024547456.
Related Concept Videos
Social Relationships and Well-Being
Traits, Mood, and Subjective Wellbeing
Neuroticism and Emotional...
Sources of Self-Esteem III: Social Comparison
Relationship Formation
Benefits of Self-Esteem
Applications of Life Tables