Related Experiment Video
Updated: Jul 14, 2026
12:42
Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
Published on: January 7, 2019
Outcomes of Talimogene Laherparepvec in Soft Tissue Sarcoma
Taylor P Williams1, Sabrina Catalano2, David A Liebner3
1Division of Surgical Oncology, The Ohio State University Medical Center, Columbus, Ohio, USA.
Journal of Surgical Oncology
|July 12, 2026
Summary
Talimogene laherparepvec (T-VEC) is an intralesional therapy for sarcoma. This case series shows T-VEC can be safely administered to patients previously treated with immune checkpoint inhibitors, potentially offering local tumor control.
Area of Science:
- Oncology
- Immunotherapy
- Virology
Background:
- Sarcoma is a rare cancer with limited treatment options.
- Talimogene laherparepvec (T-VEC) is an oncolytic immunotherapy investigated for anti-tumor immune response.
- Data on T-VEC efficacy in sarcoma, especially after immune checkpoint inhibitor (ICI) failure, is limited.
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