Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Language and Cognition01:27

Language and Cognition

Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

FMR1 gene therapy restores translationally relevant phenotypes in a mouse model for fragile X syndrome.

Gene therapy·2026
Same author

Modality-specific consolidation shapes long-term retention in statistical learning.

Psychological research·2026
Same author

Gaboxadol increases resting theta and alpha power without affecting evoked responses in fragile X syndrome in a home-based setting.

Journal of neurodevelopmental disorders·2026
Same author

Sensory-to-motor transformations: From serial pipelines to dynamic, distributed processes.

Neuroscience and biobehavioral reviews·2026
Same author

SPG601-associated modulation of resting-state EEG and improvement in executive function in a fragile X syndrome randomized controlled crossover study.

Scientific reports·2026
Same author

Acute and chronic dosing of the GABA A alpha 2,3 selective agonist BAER-101 do not alter behavior but may impact auditory-evoked EEG responses in adults with fragile X syndrome.

Scientific reports·2026

Related Experiment Video

Updated: Jul 14, 2026

Dissecting Cell-Autonomous Function of Fragile X Mental Retardation Protein in an Auditory Circuit by In Ovo Electroporation
11:10

Dissecting Cell-Autonomous Function of Fragile X Mental Retardation Protein in an Auditory Circuit by In Ovo Electroporation

Published on: July 6, 2022

Aberrant Neural Entrainment to Word-Level Speech Patterns in Fragile X Syndrome: Evidence for a Statistical Learning

Laura J Batterink1, Yanchen Liu2, Grace Westerkamp2

  • 1Department of Psychology; Western Centre for Brain and Mind, Western Institute for Neuroscience, University of Western Ontario, London, Ontario, Canada.

Autism Research : Official Journal of the International Society for Autism Research
|July 12, 2026
PubMed
Summary

Children with Fragile X syndrome (FXS) show impaired statistical learning, struggling to identify word patterns in speech. This deficit in learning speech structure may be a target for future therapies.

Keywords:
EEGauditory processingelectroencephalographyfragile X syndromelanguage developmentneural entrainmentstatistical learning

More Related Videos

Measuring Statistical Learning Across Modalities and Domains in School-Aged Children Via an Online Platform and Neuroimaging Techniques
08:05

Measuring Statistical Learning Across Modalities and Domains in School-Aged Children Via an Online Platform and Neuroimaging Techniques

Published on: June 30, 2020

TMS: Using the Theta-Burst Protocol to Explore Mechanism of Plasticity in Individuals with Fragile X Syndrome and Autism
10:58

TMS: Using the Theta-Burst Protocol to Explore Mechanism of Plasticity in Individuals with Fragile X Syndrome and Autism

Published on: December 28, 2010

Related Experiment Videos

Last Updated: Jul 14, 2026

Dissecting Cell-Autonomous Function of Fragile X Mental Retardation Protein in an Auditory Circuit by In Ovo Electroporation
11:10

Dissecting Cell-Autonomous Function of Fragile X Mental Retardation Protein in an Auditory Circuit by In Ovo Electroporation

Published on: July 6, 2022

Measuring Statistical Learning Across Modalities and Domains in School-Aged Children Via an Online Platform and Neuroimaging Techniques
08:05

Measuring Statistical Learning Across Modalities and Domains in School-Aged Children Via an Online Platform and Neuroimaging Techniques

Published on: June 30, 2020

TMS: Using the Theta-Burst Protocol to Explore Mechanism of Plasticity in Individuals with Fragile X Syndrome and Autism
10:58

TMS: Using the Theta-Burst Protocol to Explore Mechanism of Plasticity in Individuals with Fragile X Syndrome and Autism

Published on: December 28, 2010

Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Genetics

Background:

  • Fragile X syndrome (FXS) is a leading inherited cause of intellectual disability and autism spectrum disorder.
  • FXS is associated with significant language and cognitive impairments.
  • Statistical learning is crucial for language acquisition but remains unexplored in FXS.

Purpose of the Study:

  • To investigate statistical learning abilities in children with FXS.
  • To determine if children with FXS exhibit impaired neural processing of speech patterns.
  • To explore potential therapeutic targets for FXS-related language deficits.

Main Methods:

  • Used electroencephalography (EEG) to measure neural entrainment.
  • Assessed statistical learning of trisyllabic words in continuous speech.
  • Compared neural responses in children with FXS (n=17) and typically developing controls (n=31).

Main Results:

  • Children with FXS demonstrated significantly reduced neural entrainment to words compared to controls.
  • Deficits were localized to the superior temporal gyrus and transverse temporal gyrus (primary auditory cortex).
  • Syllable-level processing was preserved, but word-level integration and learning over time were impaired in FXS.

Conclusions:

  • Children with FXS have impaired statistical learning, specifically in forming word representations from syllables.
  • The findings suggest deficits in integrating auditory information rather than general auditory processing.
  • Neural entrainment to statistical structure presents a potential therapeutic target for FXS.