Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Extraction, characterization, and antimicrobial potential of Kappa-Carrageenan from Kappaphycus alvarezii with HasA-targeted molecular docking validation.

NPJ science of food·2026
Same author

Reducing Lower Extremity Amputations via Peer Support Interventions: A Scoping Review.

Journal of the American Podiatric Medical Association·2026
Same author

Allura red in aquatic systems: Treatment technologies, process intensification strategies, and future perspectives for sustainable water management.

Journal of contaminant hydrology·2026
Same author

Collaborative innovations and strategic directions in public health education: Insights from a round table discussion.

Journal of family medicine and primary care·2026
Same author

Metabolite profiling and evaluation of antioxidant, antidiabetic, and antibacterial potential of Thymus linearis Benth. supported by molecular docking and PASS prediction.

Scientific reports·2025
Same author

Structural Characterization, In Vitro Antidiabetic Activity, and Molecular Docking Studies of Isolated Compounds From Allamanda cathartica.

Chemistry & biodiversity·2025

Related Experiment Video

Updated: Jul 14, 2026

Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications
11:28

Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications

Published on: April 28, 2015

Biogenic Fe3O4 Nanoparticles Synthesized from Rubus ellipticus: Phytochemical Profiling, Structural Characterization,

Priyadarshini Chanyal1, Vibha Joshi2, Mohammad S Javed3

  • 1Department of Chemistry, D.S.B. Campus, Kumaon University, Nainital, Uttarakhand, 263002, India.

Applied Biochemistry and Biotechnology
|July 12, 2026
PubMed
Summary

Green synthesis of iron oxide nanoparticles (Fe3O4 NPs) using Rubus ellipticus leaf extract yielded nanoparticles with significant antioxidant, antidiabetic, and antibacterial properties. These eco-friendly nanoparticles show promise for various biomedical applications.

Keywords:
Rubus ellipticusAnti-bacterial activityAntidiabeticAntioxidantIron oxide nanoparticles

More Related Videos

Green Synthesis, Characterization, Encapsulation, and Measurement of the Release Potential of Novel Alkali Lignin Micro-/Submicron Particles
07:42

Green Synthesis, Characterization, Encapsulation, and Measurement of the Release Potential of Novel Alkali Lignin Micro-/Submicron Particles

Published on: March 1, 2024

Synthesis of Functionalized Magnetic Nanoparticles, Their Conjugation with the Siderophore Feroxamine and its Evaluation for Bacteria Detection
15:03

Synthesis of Functionalized Magnetic Nanoparticles, Their Conjugation with the Siderophore Feroxamine and its Evaluation for Bacteria Detection

Published on: June 16, 2020

Related Experiment Videos

Last Updated: Jul 14, 2026

Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications
11:28

Biofunctionalized Prussian Blue Nanoparticles for Multimodal Molecular Imaging Applications

Published on: April 28, 2015

Green Synthesis, Characterization, Encapsulation, and Measurement of the Release Potential of Novel Alkali Lignin Micro-/Submicron Particles
07:42

Green Synthesis, Characterization, Encapsulation, and Measurement of the Release Potential of Novel Alkali Lignin Micro-/Submicron Particles

Published on: March 1, 2024

Synthesis of Functionalized Magnetic Nanoparticles, Their Conjugation with the Siderophore Feroxamine and its Evaluation for Bacteria Detection
15:03

Synthesis of Functionalized Magnetic Nanoparticles, Their Conjugation with the Siderophore Feroxamine and its Evaluation for Bacteria Detection

Published on: June 16, 2020

Area of Science:

  • Materials Science
  • Nanotechnology
  • Green Chemistry

Background:

  • Iron oxide nanoparticles (Fe3O4 NPs) are crucial in biomedical applications.
  • Traditional synthesis methods often involve harsh chemicals and conditions.
  • Exploring sustainable and eco-friendly synthesis routes is essential.

Purpose of the Study:

  • To report the green synthesis of Fe3O4 NPs using Rubus ellipticus (RE) leaf extract.
  • To characterize the synthesized RE-mediated Fe3O4 NPs (RE-Fe).
  • To evaluate the biological activities of RE-Fe for potential biomedical applications.

Main Methods:

  • Green synthesis of Fe3O4 NPs using ethanolic RE leaf extract.
  • Phytochemical profiling of RE extract using Gas Chromatography-Mass Spectrometry (GC-MS).
  • Characterization of RE-Fe using X-ray Diffraction (XRD), Transmission Electron Microscopy-Energy Dispersive X-ray (TEM-EDX), and X-ray Photoelectron Spectroscopy (XPS).
  • Evaluation of antioxidant, antidiabetic, and antibacterial activities.
  • Molecular docking studies.

Main Results:

  • GC-MS identified 48 phytochemicals in RE extract acting as reducing and stabilizing agents.
  • XRD confirmed phase-pure magnetite with a cubic spinel structure.
  • TEM revealed quasi-spherical RE-Fe nanoparticles with an average size of 37.73 ± 6.03 nm.
  • XPS confirmed the characteristic Fe²⁺/Fe³⁺ oxidation states of Fe3O4.
  • RE-Fe exhibited excellent antioxidant activity (IC50 = 27.93 µg/mL in DPPH assay).
  • RE-Fe demonstrated strong α-amylase and α-glucosidase inhibition (IC50 = 49.54 and 35.21 µg/mL).
  • RE-Fe showed potent antibacterial activity against E. coli and S. aureus, comparable to ciprofloxacin.
  • Molecular docking supported the observed biological activities.

Conclusions:

  • Rubus ellipticus leaf extract is an effective and eco-friendly source for synthesizing Fe3O4 NPs.
  • The synthesized RE-Fe nanoparticles possess significant antioxidant, antidiabetic, and antibacterial properties.
  • These findings highlight the potential of RE-Fe NPs for diverse biomedical applications.