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Magnetic Resonance Imaging Assessment of Carcinogen-induced Murine Bladder Tumors

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Published on: March 29, 2019

Validation and Predictive Modelling of a Portable Bladder Scanner for Precision Bladder Management in Pelvic

Wenzheng Huang¹, Weiping Fu², Xinlei Zhang¹

¹Department of Radiotherapy, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 1111Xianxia Road, Shanghai, 200336.

The British Journal of Radiology

|July 13, 2026

Summary

The Caresono PadScan HD5 portable bladder scanner provides reliable bladder volume estimates for pelvic radiotherapy, reducing repeat imaging. An age-stratified protocol optimizes bladder preparation, improving efficiency and standardization.

Keywords:

bladder filling protocol bladder volume management pelvic radiotherapy portable bladder scanner predictive modelling

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A Murine Orthotopic Bladder Tumor Model and Tumor Detection System

A Murine Orthotopic Bladder Tumor Model and Tumor Detection System

Published on: January 12, 2017

Area of Science:

Radiotherapy and Medical Imaging
Urology and Bladder Management

Background:

Accurate bladder volume (BV) measurement is crucial for pelvic radiotherapy planning.
Current methods for BV assessment can be time-consuming and may lead to inconsistencies in bladder preparation.

Purpose of the Study:

To validate the accuracy of the portable Caresono PadScan HD5 bladder scanner against planning CT.
To assess the clinical utility of the HD5 scanner in optimizing bladder preparation for pelvic radiotherapy.

Main Methods:

Retrospective analysis of two cohorts: 114 patients using HD5 and 111 historical controls.
Correlation, regression, and Bland-Altman analysis to compare HD5-measured volume (VHD5) with planning CT volume (VCT).
Comparison of initial Cone-Beam CT (CBCT) repetition rates and subgroup analyses for volume and age.

Main Results:

VHD5 showed good correlation with VCT (r=0.723, P<0.001) but systematically underestimated bladder volumes (mean bias -34.39 mL).
Underestimation was more pronounced at higher bladder volumes (VCT ≥ 300 mL) and in younger patients (<65 years).
Implementation of the HD5 scanner significantly reduced initial CBCT repetition rates from 48.7% to 22.8% (P<0.001).

Conclusions:

The Caresono PadScan HD5 offers a reliable method for estimating bladder volume, despite a consistent underestimation bias.
An age-stratified, moderate-fill protocol using HD5 measurements effectively reduces repeat CBCT imaging and standardizes bladder preparation in pelvic radiotherapy.
This study translates HD5 measurements into a practical, age-stratified protocol for routine bladder management in pelvic RT.