Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 14, 2026

In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
09:56

In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model

Published on: January 21, 2018

Multicenter OCT-Based Visual Field Representations via Segmentation-Free 3D CNNs: Forecasting, Longitudinal

Makoto Koyama1, Hidenori Takahashi2,3, Satoru Inoda3

  • 1Minamikoyasu Eye Clinic, Kimitsu, Japan.

Translational Vision Science & Technology
|July 13, 2026
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same authorSame journal

Effect of Signal-Strength Filtering on 3D Convolutional Neural Network-Based Visual Field Estimation From Macular OCT.

Translational vision science & technology·2026
Same author

Aqueous humour cytokine profiles in retinal vein occlusion: a comparative study of acute, chronic recurrent, and control eyes.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
Same author

Colorectal liver metastasis with bile duct tumor thrombus discovered 15 years post primary tumor resection: a case report and literature review.

International cancer conference journal·2023
Same author

Change Impact of Body Composition During Neoadjuvant Chemoradiotherapy in Patients with Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma Undergoing Pancreatectomy.

Annals of surgical oncology·2022
Same author

ASO Author Reflections: Neoadjuvant Chemoradiotherapy for Patients with Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma Undergoing Pancreatectomy Changes Body Composition Influencing Long-term Outcomes.

Annals of surgical oncology·2022
Same author

The utility of bile juice culture analysis for the management of postoperative infection after pancreaticoduodenectomy.

Surgery·2022

Three-dimensional convolutional neural networks (3DCNNs) can create visual field (VF)-shaped representations from optical coherence tomography (OCT) scans. These OCT-based estimated VFs (OCT-VF) improve future visual field predictions and disease monitoring.

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Artificial Intelligence

Background:

  • Automated perimetry, such as Humphrey Field Analyzer (HFA), is standard for monitoring glaucoma and other visual field defects.
  • However, HFA measurements can be affected by noise and variability, potentially obscuring early signs of progression.
  • Novel methods are needed to enhance the accuracy and sensitivity of visual field monitoring.

Purpose of the Study:

  • To evaluate segmentation-free 3DCNNs for generating OCT-based estimated visual fields (OCT-VF) from macular OCT volumes.
  • To assess the performance of these OCT-VF models in forecasting future HFA measurements.
  • To characterize the longitudinal variability of OCT-VF compared to HFA data.

Main Methods:

  • Trained 3DCNN models on a large dataset of 129,007 paired OCT-HFA scans from 13,366 patients.

More Related Videos

Functional Magnetic Resonance Imaging (fMRI) of the Visual Cortex with Wide-View Retinotopic Stimulation
07:11

Functional Magnetic Resonance Imaging (fMRI) of the Visual Cortex with Wide-View Retinotopic Stimulation

Published on: December 8, 2023

Related Experiment Videos

Last Updated: Jul 14, 2026

In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
09:56

In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model

Published on: January 21, 2018

Functional Magnetic Resonance Imaging (fMRI) of the Visual Cortex with Wide-View Retinotopic Stimulation
07:11

Functional Magnetic Resonance Imaging (fMRI) of the Visual Cortex with Wide-View Retinotopic Stimulation

Published on: December 8, 2023

  • Evaluated forecasting accuracy using HFA-only models and hybrid models (AOS-AVG) incorporating OCT-VF.
  • Assessed longitudinal variability by analyzing residual deviations from linear trends.

    • Main Results:

    • Hybrid forecasting models (AOS-AVG) significantly reduced mean absolute error compared to HFA-only forecasts.
    • OCT-VF demonstrated significantly lower residual variability than HFA measurements.
    • Eyes identified as progressing by OCT-VF but not HFA showed greater variability and faster HFA MD decline.

    Conclusions:

    • Hybrid forecasting incorporating OCT-VF-derived slopes enhances prediction of future visual field outcomes.
    • The reduced variability of OCT-VF may help detect progression signals masked by perimetric noise.
    • OCT-VF shows potential as a complementary tool for precision disease monitoring in ophthalmology.