Related Experiment Video
Updated: Jul 14, 2026

Bovine Mammary Gland Biopsy Techniques
Published on: December 23, 2018
Mechanisms by Which Plant Extracts Ameliorate Bovine Mastitis Through the Regulation of Mitochondrial Function: A
Zhuojia Li1, Jie Song2, Changjin Ao1
1Key Laboratory of Animal Nutrition and Feed Science, College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.
Abstract:
Mastitis is recognized worldwide as one of the most expensive and common bovine diseases, severely affecting bovine health and milk quality. Mitochondria, known to play important roles in bovine mammary epithelial cells (BMECs), not only provide energy for milk synthesis but also participate in the regulation of the intracellular redox balance, inflammatory reactions, calcium signal transduction, and apoptosis. Mastitis destroys the dynamic balance between the intrinsic repair and damage mechanisms of mitochondria, which leads to mitochondrial dysfunction and aggravation of mammary cell injury or apoptosis. Plant extracts are rich in bioactive substances and are promising antibiotic substitutes for alleviating bovine mastitis. This paper reviews the mechanism through which plant extracts promote mitochondrial repair by interfering with mitophagy, dynamic balance and biogenesis, and alleviate mitochondrial damage by inhibiting mitochondrial ROS, calcium homeostasis imbalance and permeability changes, resulting in the regulation of the mitochondrial function of mammary cells under inflammation and oxidative stress. Elucidation of these mechanisms can provide new strategies for the targeted control of bovine mastitis.
More Related Videos
08:29Measuring Liver Mitochondrial Oxygen Consumption and Proton Leak Kinetics to Estimate Mitochondrial Respiration in Holstein Dairy Cattle
Published on: November 30, 2018
08:03Unveiling Xenobiotic Transport and Effects in Isolated Mitochondria: Insights from Respirometric and Enzymatic Assays
Published on: March 7, 2025
Related Concept Videos
Overview of Metabolism
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
Clinical Significance of Antibiotic Resistance
Mitochondria
ATP Synthase: Mechanism
Translocation of Proteins into the Mitochondria
Sorting of outer membrane proteins:
Mitochondrial outer membrane proteins are of two types: the transmembrane, beta-barrel porins, and the membrane-anchored, alpha-helical proteins. Beta-barrel porin precursors are translocated by the TOM complex and inserted into the outer mitochondrial membrane by the SAM complex. In contrast,...
Mitochondrial Membranes