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Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury
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Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury

Published on: May 27, 2022

Limitations in the Use of Plasma Biomarkers of Brain Injury

Ari R Joffe1, Natalie R Anton1, Jonathan P Duff1

  • 1Department of Pediatrics, Division of Pediatric Critical Care, University of Alberta, Edmonton, Alberta, Canada.

JAMA Pediatrics
|July 13, 2026
PubMed
Abstract

No abstract available in PubMed .

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Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
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Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...

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