Kimura disease presenting as a right lower limb soft tissue tumor: a case report

Kimura disease (KD) is a rare chronic inflammatory disorder. Its pathogenesis remains unclear but is believed to involve dysregulated immune responses. It is characterized by soft tissue masses in the head and neck, elevated eosinophil counts in peripheral blood, and elevated serum IgE levels. This case report describes a 53-year-old Asian male who presented with a localized mass on the anterior aspect of the right lower leg without abnormalities in peripheral blood. Additionally, eight articles published between 2015 and 2025 were reviewed, summarizing 12 patient cases to identify common aspects in diagnosing and treating KD, primarily characterized by limb lesions.