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Published on: September 20, 2018
Chronic Headache and Visual Field Loss: Manifestations in a Patient With Chronic Brucellosis Meningitis: Case Report
1Department of Infectious Diseases, School of Medicine, Arak University of Medical Sciences, Arak, Iran, arakmu.ac.ir.
Abstract:
Brucellosis is a zoonotic infection caused by Brucella species, often leading to serious complications and presenting diagnostic challenges. A 45-year-old female patient presented with a headache that had persisted for two months and was recently accompanied by visual disturbances. Notably, the patient's headache began 6 weeks postpartum, and she had no prior history of illness, medication use, or headaches. Imaging studies were normal, and cerebrospinal fluid (CSF) analysis revealed meningitis, with a positive Wright test. After excluding other potential causes and considering the patient's consumption of local dairy products, the diagnosis of Brucella meningitis was confirmed. The patient was treated with a standard three-drug regimen for 6 months and was followed throughout the treatment period. Initially, her headache resolved, followed by improvement in visual symptoms. Follow-up serologic tests showed a declining trend in Brucella titers, and perimetry results returned to normal by the fourth month of treatment. This case underscores the importance of including Brucella in the differential diagnosis of patients with chronic meningitis, especially in endemic regions, and highlights the favorable outcomes associated with prompt treatment.
Insights
Brucellosis meningitis, a challenging zoonotic infection, can cause chronic headaches and visual issues. Prompt diagnosis and a six-month treatment regimen led to a full recovery in a postpartum patient.
Area of Science:
- Infectious Diseases
- Neurology
- Public Health
Background:
- Brucellosis is a significant zoonotic disease with diverse clinical presentations.
- Neurological complications, such as meningitis, pose diagnostic challenges.
- Postpartum onset of symptoms requires careful consideration of infectious etiologies.
Purpose of the Study:
- To report a case of Brucella meningitis in a postpartum woman.
- To highlight diagnostic considerations for chronic meningitis.
- To emphasize the importance of early treatment and its outcomes.
Main Methods:
- Case report of a 45-year-old female with persistent headache and visual disturbances.
- Diagnostic workup included neuroimaging and cerebrospinal fluid (CSF) analysis.
- Wright test confirmed Brucella infection; differential diagnosis was established.
Main Results:
- CSF analysis revealed meningitis with a positive Wright test.
- The patient consumed local dairy products, suggesting a potential exposure route.
- Successful treatment with a standard three-drug regimen for six months resulted in symptom resolution and normalization of serologic titers and visual fields.
Conclusions:
- Brucella meningitis should be considered in the differential diagnosis of chronic meningitis, particularly in endemic areas.
- Early diagnosis and appropriate antibiotic therapy lead to favorable patient outcomes.
- This case highlights the importance of considering zoonotic infections in postpartum patients with neurological symptoms.
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