Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the cerebellum's...
Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluating the relationship of exposure to adverse childhood experiences and pain in healthy subjects.

Fortschritte der Neurologie-Psychiatrie·2026
Same author

High-resolution kitsch by AI: Why society needs art, not more AI content.

Perception·2026
Same author

Accessing the Digital Health Application (DiGA) Market: Key Success Factors, Market Barriers and Strategies for Sustainable Adoption.

Inquiry : a journal of medical care organization, provision and financing·2026
Same author

The communicative Umwelt for creative design, addressing the psychology of sustainability, to solve future global challenges.

Frontiers in psychology·2026
Same author

Effects of Cancer Treatment on Somatosensory and Nociceptive Processing in Children and Adolescents: A Systematic Review.

Pediatric blood & cancer·2026
Same author

Motor-evoked pain on a background of widespread muscle strain: a novel model simulating everyday activities.

Scandinavian journal of pain·2026

Related Experiment Video

Updated: Jul 15, 2026

A Fine Motor Task to Study Joint Kinematics in a Preclinical Model of Neurodegenerative Disease
05:39

A Fine Motor Task to Study Joint Kinematics in a Preclinical Model of Neurodegenerative Disease

Published on: June 13, 2025

Pain differences in cognitive impairment appear only during active motor tasks.

Stefan Lautenbacher1, Vivien Schreiber2, Clemens Grupp3

  • 1Department of Medical Psychology and Sociology, Medical Faculty, University of Augsburg, Augsburg, Germany.

Frontiers in Pain Research (Lausanne, Switzerland)
|July 13, 2026
PubMed
Summary

Cognitive impairment in older adults is linked to increased movement-related pain during daily activities. This suggests that reduced cognitive function impacts how pain is experienced during physical tasks.

Keywords:
dementiaexperimental painimpaired cognitionliving labmovement planningmovement-related pain

More Related Videos

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
07:42

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

Related Experiment Videos

Last Updated: Jul 15, 2026

A Fine Motor Task to Study Joint Kinematics in a Preclinical Model of Neurodegenerative Disease
05:39

A Fine Motor Task to Study Joint Kinematics in a Preclinical Model of Neurodegenerative Disease

Published on: June 13, 2025

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
07:42

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients

Published on: December 16, 2022

Area of Science:

  • Gerontology
  • Neuroscience
  • Pain Research

Background:

  • Cognitive impairment in older adults is inconsistently associated with altered pain processing and increased pain vulnerability.
  • The impact of cognitive status on pain perception, particularly movement-related pain in real-world contexts, requires further investigation.

Purpose of the Study:

  • To investigate the hypothesis that cognitive impairment more significantly affects movement-related pain in everyday contexts compared to pain sensitivity in laboratory settings.
  • To compare pain experiences during motor tasks and experimental pain assessments between cognitively healthy and cognitively impaired older adults.

Main Methods:

  • Utilized the CERAD scale (Consortium to Establish a Registry for Alzheimer's Disease) to classify 76 older adults (38 cognitively healthy, 38 cognitively impaired) into groups matched for age and sex.
  • Assessed pain intensity (NRS) during standardized motor tasks (walking, bed mobility, lifting) and experimental pressure/heat pain sensitivity.
  • Collected data on perceived exertion during motor tasks and clinical pain status via structured interviews.

Main Results:

  • No significant differences were found between groups in baseline clinical pain or experimental pain sensitivity.
  • Cognitively impaired participants reported significantly higher movement-related pain during the motor tasks.
  • Cognitive status (CERAD classification) explained significant additional variance in movement-related pain, beyond clinical pain and experimental pain sensitivity.

Conclusions:

  • Reduced cognitive functioning is a significant predictor of increased pain during active, everyday motor tasks in older adults.
  • This association may stem from diminished capacities for pain-minimizing movement strategies, including recall, planning, and execution.
  • Findings highlight the importance of assessing pain within behaviorally relevant contexts to understand pain mechanisms in older adults with cognitive impairment.