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Synchronous Presentation of Intraperitoneal and Retroperitoneal Dedifferentiated Liposarcoma: A Case Report.
Yousra Mhande1, Laila Merghat1, Amal Hajri2,1
1General Surgery, Faculty of Medicine and Pharmacy, Hassan II University, Casablanca, MAR.
Cureus
|July 13, 2026
Summary
This case report details a rare combined intraperitoneal and retroperitoneal dedifferentiated liposarcoma (DDLPS). The study highlights diagnostic and treatment challenges, emphasizing MDM2 analysis for complex liposarcoma cases.
Area of Science:
- Oncology
- Surgical Pathology
Background:
- Liposarcomas (LPS) are malignant tumors with varying aggressiveness and common retroperitoneal origins.
- Intraperitoneal liposarcoma is rare, often presenting with nonspecific symptoms, posing diagnostic challenges.
- Dedifferentiated liposarcoma (DDLPS) is an aggressive subtype requiring careful management.