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Related Experiment Video

Updated: Jul 15, 2026

Functional Assessment of Intestinal Permeability and Neutrophil Transepithelial Migration in Mice using a Standardized Intestinal Loop Model

Functional Assessment of Intestinal Permeability and Neutrophil Transepithelial Migration in Mice using a Standardized Intestinal Loop Model

Published on: February 11, 2021

[Construction of a Segmented PMI Estimation Model Integrating Intestinal Microbial Signatures and Machine Learning in

Xiangyan Zhang¹, Fan Yang², Sheng Hu²

¹Department of Forensic Medicine, Xiangya School of Basic Medical Sciences, Central South University, Changsha 410013, China.

Fa Yi Xue Za Zhi

|July 13, 2026

Summary

Changes in gut bacteria after death offer clues for estimating time since death. A new segmented regression model using "rupture points" in microbial changes significantly improves postmortem interval (PMI) estimation accuracy in mice.

Area of Science:

Forensic microbiology
Decomposition studies
Microbial ecology

Keywords:

forensic pathology intestinal microbiota machine learning nude mice postmortem interval estimation segmented regression model

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