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Growth of Cartilage and Bone Tissue

Growth of Cartilage and Bone Tissue

Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...

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Related Experiment Video

Updated: Jul 15, 2026

$Autologous Microfractured and Purified Adipose Tissue for Arthroscopic Management of Osteochondral Lesions of the Talus$

Autologous Microfractured and Purified Adipose Tissue for Arthroscopic Management of Osteochondral Lesions of the Talus

Published on: January 23, 2018

Cartilage Injury: Update on Diagnosis and Image-guided Therapy.

Josue Solís-Ugalde¹, Teodoro Martín-Noguerol², M Luisa Nieto-Morales³

¹Department of Radiology, Traumatology Hospital, San José 40104, Costa Rica.

Magnetic Resonance Imaging Clinics of North America

|July 13, 2026

Summary

Magnetic resonance (MR) imaging is crucial for evaluating cartilage injuries and osteoarthritis. Advanced MR techniques offer detailed insights for diagnosis, treatment, and monitoring of cartilage conditions.

Keywords:

Cartilage injury Compositional MR imaging Image-guided therapy MR imaging

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Clinical Protocol of Producing Adipose Tissue-Derived Stromal Vascular Fraction for Potential Cartilage Regeneration

Clinical Protocol of Producing Adipose Tissue-Derived Stromal Vascular Fraction for Potential Cartilage Regeneration

Published on: September 29, 2018

Area of Science:

Orthopedics and Sports Medicine
Radiology
Biomedical Engineering

Background:

Cartilage injuries are common causes of pain and disability, often leading to osteoarthritis.
Osteoarthritis is a degenerative joint disease affecting millions worldwide.
Early detection and accurate assessment of cartilage damage are vital for effective management.

Purpose of the Study:

To review the current state of MR imaging for cartilage evaluation.
To summarize MR imaging techniques for detecting and grading cartilage lesions.
To explore the role of MR imaging in guiding therapies and monitoring outcomes.

Main Methods:

Comprehensive review of current literature on MR imaging of cartilage.
Analysis of MR imaging sequences, quantitative techniques, and classification systems.
Discussion of image-guided therapies and postoperative evaluation.

Main Results:

MR imaging provides high-resolution morphologic and quantitative data for cartilage assessment.
Established classification systems correlate MR imaging findings with arthroscopic results.
Emerging AI and functional MR imaging show promise for enhanced diagnosis and monitoring.

Conclusions:

MR imaging is the gold standard for cartilage evaluation, aiding in early diagnosis and treatment planning.
Advanced and AI-enhanced MR techniques are expanding the potential for managing cartilage injuries and osteoarthritis.
Accurate MR imaging assessment is essential for guiding interventions and evaluating treatment success.