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Published on: February 28, 2025
Exploratory study on the association between oral functions and nailfold capillary parameters.
Kyoko Miura-Sugano1, Atsuhiro Nagasaki2, Hiroshi Kunikata3
1Division of Molecular and Regenerative Prosthodontics, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai-city, 980-8575, Miyagi, Japan.
Scientific Reports
|July 13, 2026
Summary
Oral frailty, including tooth loss and dry mouth, may impact blood vessel health in the fingers. Further research is needed to confirm these preliminary findings on oral health and systemic connections.
Area of Science:
- Gerontology
- Oral Medicine
- Microcirculation
Background:
- Extending life expectancy is a key public health goal.
- Oral frailty is linked to overall systemic health.
- The connection between oral function and nailfold capillary parameters is not well understood.
Purpose of the Study:
- To investigate the association between oral function parameters and nailfold capillary characteristics.
- To explore potential links between oral health and microvascular changes.
Main Methods:
- Analysis of data from 311 participants (mean age 55.66 years).
- Evaluation of oral parameters: number of remaining teeth, tongue pressure, and oral mucosal moisture.
- Assessment of nailfold capillary parameters: number, length, width, and turbidity.
Main Results:
- A significant association was observed between the number of remaining teeth and capillary number.
- Oral mucosal moisture showed significant associations with capillary turbidity and width.
- These associations were not statistically significant after P-value adjustment and are considered preliminary.
Conclusions:
- Findings suggest potential links between specific oral functions and nailfold capillary parameters.
- These results provide a basis for hypothesis-generating research on oral-systemic health connections.
- Further investigation into oral health's role in systemic conditions and potential diagnostic applications is warranted.
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