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Updated: Jul 15, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
AI agents in clinical practice: an evidence map
Joy Xu1, Justin M Ko2, Joseph C Kvedar3
1David Geffen School of Medicine, Los Angeles, CA, USA. joyxu@mednet.ucla.edu.
Abstract:
The rapid emergence of autonomous AI systems (agentic AI) marks a pivotal inflection point in digital medicine. This perspective synthesizes evidence across diagnostics, management, and care-adjacent operations to identify opportunities for adoption. Early deployments are concentrated in administrative workflows, though agentic applications are rapidly expanding across the clinical patient journey. Proactive governance, auditability, and clinician oversight are essential for responsible agent translation into clinical practice.
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