Temporal Changes in Continuous Glucose Monitoring Profiles in Health Care Workers Participating in a Digitally...

Area of Science:

• Metabolic health
• Digital health interventions
• Occupational health

Background:

• Health care workers have high cardiometabolic risks due to demanding schedules and stress.
• Limited targeted interventions exist for this population.
• An 8-week digital Metabolic Wellness Program (MWP) using lifestyle education and continuous glucose monitoring (CGM) was evaluated.

Purpose of the Study:

• To assess the impact of a digital Metabolic Wellness Program (MWP) on glycemic control and behavioral changes in health care workers.
• To evaluate both static and novel temporal CGM-derived metrics.
• To explore correlations between program engagement, behavioral changes, and glycemic improvements.

Main Methods:

• 100 health care workers and dependents participated in the 8-week MWP.
• Participants were stratified by baseline time in tight range (TITR).
• CGM metrics (AG, GRI, TIR, TITR, CV) were analyzed using static and temporal change metrics (MCI, ICI).

Main Results:

• No significant cohort-wide static glycemic changes were observed.
• Temporal metrics revealed significant improvements, particularly in the low TITR group (e.g., AG MCI -17.2 mg/dL, GRI MCI -15.3).
• MWP engagement correlated with positive behavioral changes and improved temporal glycemic metrics (e.g., TIR MCI: r = 0.31).

Conclusions:

• The digital MWP demonstrated significant behavioral and temporal glycemic improvements, especially in participants with lower baseline TITR.
• Static CGM metrics did not show significant changes.
• Further research is needed to determine the long-term sustainability of these improvements.