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Updated: Jul 15, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
Obesity Remission: A Missing Target in Contemporary Medicine
Theocharis Koufakis1, Alexander Kokkinos2, Luca Busetto3
1Second Propaedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration General Hospital, Thessaloniki, Greece.
This study proposes a new remission-oriented approach for obesity management, shifting from merely slowing progression to achieving sustained remission. This framework aims for better outcomes and reduced healthcare burden by prioritizing early, effective interventions.
Area of Science:
- Endocrinology
- Metabolic Diseases
- Public Health
Background:
- Obesity is a chronic disease with significant health and economic impacts.
- Current obesity treatments are often conservative, delaying effective interventions.
- Other chronic diseases utilize remission-oriented strategies.
Purpose of the Study:
- To propose a remission-oriented paradigm for obesity management.
- To define obesity remission as a multidimensional, sustained state.
- To introduce an induction-remission-maintenance model for obesity.
Main Methods:
- Conceptual framework development.
- Literature review of chronic disease management strategies.
- Defining multidimensional criteria for obesity remission.
Main Results:
- Obesity remission is defined as achieving adiposity targets, resolving complications, restoring function, and improving well-being.
- Remission is conceptualized as a continuum, potentially maintained with pharmacotherapy.
- An induction-remission-maintenance model is proposed for early, effective intervention.
Conclusions:
- A remission-oriented approach offers a structured model for obesity management.
- This paradigm can improve clinical outcomes and reduce healthcare burden.
- Long-term monitoring and disease surveillance are crucial even with effective therapies.
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