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Bioplastics01:27

Bioplastics

Bioplastics derived from microbial processes present a sustainable alternative to conventional petroleum-based plastics. Among these, polyhydroxyalkanoates (PHAs), particularly polyhydroxybutyrates (PHBs), have emerged as prominent candidates due to their biodegradability and biocompatibility. These polymers are synthesized by a variety of bacteria, such as Cupriavidus necator and Pseudomonas putida, which naturally accumulate PHAs as intracellular carbon and energy reserves, especially under...
Site-Targeted Drug Delivery Systems: Polymeric Carriers01:24

Site-Targeted Drug Delivery Systems: Polymeric Carriers

Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...

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Related Experiment Video

Updated: Jul 15, 2026

4D Printed Bifurcated Stents with Kirigami-Inspired Structures
06:52

4D Printed Bifurcated Stents with Kirigami-Inspired Structures

Published on: July 25, 2019

Biodegradable polymer-based stents: materials, design, and biomedical applications.

Gamze Dik1, Büşra Bakar1, Kübra Karadaş Gedik1

  • 1Biochemistry and Biomaterials Research Laboratory, Department of Chemistry, Faculty of Arts and Science, İnönü University Malatya 44280 Türkiye ahmet.ulu@inonu.edu.tr burhan.ates@inonu.edu.tr.

RSC Advances
|July 14, 2026
PubMed
Summary

Biodegradable polymeric stents offer a promising alternative to traditional metal stents for cardiovascular disease treatment. Their biocompatibility, customizable properties, and controlled degradation eliminate the need for repeat surgeries.

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Last Updated: Jul 15, 2026

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Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Cardiovascular Engineering

Background:

  • Metal stents, while effective, present challenges like corrosion, inflammation, and restenosis.
  • These limitations necessitate the exploration of alternative stent materials.
  • Polymeric stents have emerged as a viable alternative due to their unique advantages.

Purpose of the Study:

  • To systematically review and classify polymer-based stents in the scientific literature.
  • To detail the types of polymers utilized, their synthesis and production methodologies.
  • To explore the biomedical application areas of polymeric stents.

Main Methods:

  • Comprehensive literature search for polymer-based stent research.
  • Systematic classification of identified polymeric stents.
  • Detailed analysis of polymer types, fabrication techniques, and applications.

Main Results:

  • Polymeric stents offer advantages such as biodegradability, biocompatibility, and tunable mechanical properties.
  • Customization of degradation rate and drug release profiles is achievable by combining polymers.
  • Diverse synthesis and production methods allow for varied geometries and functional formulations.

Conclusions:

  • Biodegradable polymeric stents represent a significant advancement in cardiovascular treatment.
  • They offer a safer alternative to metal stents, reducing complications and the need for re-intervention.
  • This review provides a foundational knowledge base for future research and development in polymeric stents.