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Identification of Clofibric Acid as a Synoviolin (SYVN1) Ligand for Proteolysis-Targeting Chimera (PROTAC)

Julia Warren1, Anandarao Munakala1, Keith D Zientek2

  • 1Program in Chemical Biology, Department of Chemical Physiology and Biochemistry, Oregon Health & Science University, 3181 SW Sam Jackson Park Rd, Portland, Oregon 97239, United States.

ACS Medicinal Chemistry Letters
|July 14, 2026
PubMed

Keywords:
E3 ligasePROTACSYVN1chemoproteomics, degradationclofibric acid

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